Ultrafast processes in light-absorbing proteins have been implicated in the primary step in
the light-to-energy conversion and the initialization of photoresponsive biological functions …

Artificial intelligence-based protein structure prediction approaches have had a
transformative effect on biomolecular sciences. The predicted protein models in the …

The Rhizoclosmatium globosum genome encodes three rhodopsin-guanylyl cyclases
(RGCs), which are predicted to facilitate visual orientation of the fungal zoospores. Here, we …

In optogenetics, light-sensitive proteins are specifically expressed in target cells and light is
used to precisely control the activity of these proteins at high spatiotemporal resolution …

Protein-chromophore interactions are a central component of a wide variety of critical
biological processes such as color vision and photosynthesis. To understand the …

The photoisomerization of the retinal chromophore of visual pigments proceeds along a
complex reaction coordinate on a multidimensional surface that comprises a hydrogen-out …

The Automatic Rhodopsin Modeling (ARM) protocol has recently been proposed as a tool
for the fast and parallel generation of basic hybrid quantum mechanics/molecular mechanics …

Susana Blanco, Juan C. López,* Santiago Mata, and JosØ L. Alonso g-Aminobutyric acid
(GABA) is arguably the most important inhibitory neurotransmitter in the brain and …

A series of enzymes for Kemp elimination of 5-nitrobenzisoxazole has been recently
designed and tested. In conjunction with the design process, extensive computational …

Protein reengineering of cellular retinoic acid binding protein II (CRABPII) has yielded a
genetically addressable system, capable of binding a profluorophoric chromophore that …