Ischemic stroke, which accounts for 75–80% of all strokes, is the predominant cause of
morbidity and mortality worldwide. The post-stroke immune response has recently emerged …

Patients with systemic lupus erythematosus (SLE) frequently show symptoms of central
nervous system (CNS) involvement, termed neuropsychiatric SLE (NPSLE). The CNS …

The immune response after stroke is known to play a major role in ischemic brain
pathobiology. The inflammatory signals released by immune mediators activated by brain …

Recent works in the area of stroke and brain ischemia has demonstrated the significance of
the inflammatory response accompanying necrotic brain injury. Acutely, this response …

Brain infarction causes tissue death by ischemia due to occlusion of the cerebral vessels
and recent work has shown that post stroke inflammation contributes significantly to the …

TWEAK is a multifunctional cytokine that controls many cellular activities including
proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK …

Stroke is a frequent cause of long-term disability and death worldwide. Ischemic stroke is
more commonly encountered compared to hemorrhagic stroke, and leads to tissue death by …

Perinatal insults such as hypoxia–ischemia induces secondary brain injury. In order to
develop the next generation of neuroprotective therapies, we urgently need to understand …

Background and Purpose—Adult stem cell therapy is an experimental stroke treatment.
Here, we assessed homing and anti-inflammatory effects of bone marrow stromal cells …

First described as a weak apoptosis inducer, the TNF superfamily ligand TWEAK has since
emerged as a cytokine that regulates multiple cellular responses, including proinflammatory …