[HTML][HTML] Trauma‐induced coagulopathy: the past, present, and future

LZ Kornblith, HB Moore, MJ Cohen - Journal of thrombosis and …, 2019 - Elsevier
Trauma remains a leading cause of death worldwide, and most early preventable deaths in
both the civilian and military settings are due to uncontrolled hemorrhage, despite paradigm …

The European guideline on management of major bleeding and coagulopathy following trauma

R Rossaint, A Afshari, B Bouillon, V Cerny… - Critical Care, 2023 - Springer
Background Severe trauma represents a major global public health burden and the
management of post-traumatic bleeding continues to challenge healthcare systems around …

Safety profile and impact of low-titer group O whole blood for emergency use in trauma

J Williams, N Merutka, D Meyer, Y Bai… - Journal of Trauma …, 2020 - journals.lww.com
PURPOSE Following US military implementation of a cold-stored whole blood program,
several US trauma centers have begun incorporating uncrossmatched, group O cold-stored …

Slowing decline in blood collection and transfusion in the United States–2017

JM Jones, MRP Sapiano, AA Savinkina, KA Haass… - …, 2020 - Wiley Online Library
INTRODUCTION The National Blood Collection and Utilization Survey (NBCUS) has
demonstrated declines in blood collection and transfusion in the United States since 2008 …

Platelet-mimicking procoagulant nanoparticles augment hemostasis in animal models of bleeding

UDS Sekhon, K Swingle, A Girish, N Luc… - Science translational …, 2022 - science.org
Treatment of bleeding disorders using transfusion of donor-derived platelets faces logistical
challenges due to their limited availability, high risk of contamination, and short (5 to 7 days) …

Resuscitation fluid choices to preserve the endothelial glycocalyx

EM Milford, MC Reade - Critical Care, 2019 - Springer
This article is one of ten reviews selected from the Annual Update in Intensive Care and
Emergency Medicine 2019. Other selected articles can be found online at https://www …

Platelet-derived-extracellular vesicles promote hemostasis and prevent the development of hemorrhagic shock

E Lopez, AK Srivastava, J Burchfield, YW Wang… - Scientific Reports, 2019 - nature.com
Every year more than 500,000 deaths are attributed to trauma worldwide and severe
hemorrhage is present in most of them. Transfused platelets have been shown to improve …

[HTML][HTML] Whole blood resuscitation and association with survival in injured patients with an elevated probability of mortality

JL Sperry, BA Cotton, JF Luther… - Journal of the …, 2023 - journals.lww.com
BACKGROUND: Low-titer group O whole blood (LTOWB) resuscitation is becoming
common in both military and civilian settings and may represent the ideal resuscitation …

[HTML][HTML] Platelet‐inspired nanomedicine in hemostasis thrombosis and thromboinflammation

S Raghunathan, J Rayes, AS Gupta - Journal of Thrombosis and …, 2022 - Elsevier
Platelets are anucleate cell‐fragments derived predominantly from megakaryocytes in the
bone marrow and released in the blood circulation, with a normal count of 150 000–40 000 …

Histone H4 induces platelet ballooning and microparticle release during trauma hemorrhage

P Vulliamy, S Gillespie, PC Armstrong… - Proceedings of the …, 2019 - National Acad Sciences
Trauma hemorrhage is a leading cause of death and disability worldwide. Platelets are
fundamental to primary hemostasis, but become profoundly dysfunctional in critically injured …