Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a life-threatening,
immunologically mediated, and usually drug-induced disease with a high burden to …

Toxic epidermal necrolysis (TEN) is an unpredictable, life-threatening drug reaction
associated with a 30% mortality. Massive keratinocyte apoptosis is the hallmark of TEN …

Stevens–Johnson syndrome and toxic epidermal necrolysis are severe cutaneous adverse
reactions that are of major concern because of high mortality rates. On the basis of data …

JKGD has received grant/research support from Dompee and SiFi. MRA-J. has done
commissioned work for Genus Pharmaceuticals; received sponsorship from AbbVie …

Background It was proposed that Stevens-Johnson syndrome and toxic epidermal
necrolysis differed from erythema multiforme majus by the pattern and localization of skin …

Importance Antibiotics are an important risk for Stevens-Johnson syndrome and toxic
epidermal necrolysis (SJS/TEN), which are the most severe types of drug hypersensitivity …

Severe skin adverse drug reactions can result in death. Toxic epidermal necrolysis (TEN)
has the highest mortality (30-35%); Stevens-Johnson syndrome and transitional forms …

Objectives: The aims of this review are to summarize the definitions, causes, and clinical
course as well as the current understanding of the genetic background, mechanism of …

Toxic epidermal necrolysis (TEN) is a potentially fatal disorder that involves large areas of
skin desquamation. Patients with TEN are often referred to burn centers for expert wound …

Toxic epidermal necrolysis (TEN) is a rare disorder characterized by extensive epidermal
death. Almost all cases appear to be caused by an idiosyncratic drug reaction. Proposed …