Therapeutic drug monitoring (TDM) is the quantification and interpretation of drug
concentrations in blood to optimize pharmacotherapy. It considers the interindividual …

Psychiatric genomics is providing insights into the nature of psychiatric conditions that in
time should identify new drug targets and improve patient care. Less attention has been paid …

ABSTRACT Introduction: Second-generation antipsychotics (SGAs) are frequently co-
prescribed with drug metabolic inducers and inhibitors. SGA pharmacokinetic drug-drug …

Rationale In psychiatric clinical practice, there is a need to identify psychotropic drugs
whose metabolisms are prone to be altered with increased inflammatory activity in an …

Both inflammation and smoking can influence a drug's pharmacokinetic properties, ie, its
liberation, absorption, distribution, metabolism, and elimination. Depending on, eg …

Inter-individual differences in antidepressant drug concentrations attained in blood may limit
the efficacy of pharmacological treatment of depressive disorders. Therapeutic drug …

At least 170 approved drugs are linked to QT prolongation, which can lead to serious
adverse drug reactions (ADRs), such as Torsade de Pointes (TdP). The aim of this study was …

Background Poor adherence to medication regimens and medical record inconsistencies
result in incomplete knowledge of medication therapy in polypharmacy patients. By …

Due to the high number of psychotropic drugs with anticholinergic potential, patients taking
psychotropic drugs are at high risk for anticholinergic adverse drug reactions (ADRs). The …

Introduction Many antidepressants cause QT prolongation but the classification of cardiac
risk of these drugs varies markedly in different published lists. This retrospective study …