To discover new molecules or review the biological activity and toxicity of therapeutic
substances, drug development, and research relies on robust biological systems to obtain …

A great challenge in neuroscience is understanding how activity in the brain gives rise to
behavior. The zebrafish is an ideal vertebrate model to address this challenge, thanks to the …

The developing brain is extremely sensitive to many chemicals. Exposure to neurotoxicants
during development has been implicated in various neuropsychiatric and neurological …

Visual stimuli can evoke complex behavioral responses, but the underlying streams of
neural activity in mammalian brains are difficult to follow because of their size. Here, I review …

Testing of compounds for neurotoxicity has become increasingly important in recent years. It
has been shown that neurological disorders like autism may be related to chemical …

Background: Per-and polyfluoroalkyl Substances (PFAS) are synthetic chemicals widely
detected in humans and the environment. Exposure to perfluorooctanesulfonic acid (PFOS) …

Copper ions are essential for biological function yet are severely detrimental when present
in excess. At the molecular level, copper ions catalyze the production of hydroxyl radicals …

Zebrafish (Danio rerio) have become popular as model organism in research. Many strains
are readily available, which not only differ morphologically, but also genetically …

The present paper describes the vibrational startle response assay (VSRA), a new robust,
simple and automated in vivo medium-to high-throughput procedure for assessment of the …

Perfluorooctane sulfonate (PFOS) is a widely spread environmental contaminant. It
accumulates in the brain and has potential neurotoxic effects. The exposure to PFOS has …