Simple Summary MicroRNAs (miRNAs) regulate messenger RNA (mRNA) expression at the
post-transcriptional level. They play an important role within physiological and pathological …

Abstract Transforming Growth Factor-beta (TGF-β) is a multifunctional cytokine that exerts its
biological effects through a complex process of activation and signaling. Initially synthesized …

Transforming growth factor β (TGF-β), a pluripotent cytokine and a multifunctional growth
factor has a crucial role in varied biological mechanisms like invasion, migration, epithelial …

There is growing evidence that germline mutations in certain genes influence cancer
susceptibility, tumor evolution, as well as clinical outcomes. Identification of a disease …

Cancer is a complex disease, initiated and sustained by the interplay of germline and
somatic mutations and environmental factors. Understanding the phenotypic consequences …

Of all cancers that affect women, the highest number of deaths results from breast cancer
(BC). The tumorigenesis of BC is due to either chromosomal instability (CIN) or genetic …

Chronic low-grade inflammation plays a role in the pathogenesis of several chronic
diseases including cancer. exercise training have been supposed to modulate inflammatory …