Mechanisms of immune suppression by myeloid-derived suppressor cells: the role of interleukin-10 as a key immunoregulatory cytokine
Chronic immune activation and inflammation are unwanted consequences of many
pathological conditions, since they could lead to tissue damage and immune exhaustion …
pathological conditions, since they could lead to tissue damage and immune exhaustion …
Interactions of HIV and antiretroviral therapy with neutrophils and platelets
M Madzime, TM Rossouw, AJ Theron… - Frontiers in …, 2021 - frontiersin.org
Neutrophils are important components of the innate immune system that mediate pathogen
defense by multiple processes including phagocytosis, release of proteolytic enzymes …
defense by multiple processes including phagocytosis, release of proteolytic enzymes …
[HTML][HTML] Neutrophils promote T-cell activation through the regulated release of CD44-bound Galectin-9 from the cell surface during HIV infection
The interaction of neutrophils with T cells has been the subject of debate and controversies.
Previous studies have suggested that neutrophils may suppress or activate T cells. Despite …
Previous studies have suggested that neutrophils may suppress or activate T cells. Despite …
The role of IL‐1β during human immunodeficiency virus type 1 infection
MM Yaseen, NM Abuharfeil… - Reviews in Medical …, 2023 - Wiley Online Library
Abstract Interleukin (IL)‐1β is a key innate cytokine that is essential for immune activation
and promoting the inflammatory process. However, abnormal elevation in IL‐1β levels has …
and promoting the inflammatory process. However, abnormal elevation in IL‐1β levels has …
The role of catecholamines in HIV neuropathogenesis
R Nolan, PJ Gaskill - Brain research, 2019 - Elsevier
The success of anti-retroviral therapy has improved the quality of life and lifespan of HIV+
individuals, transforming HIV infection into a chronic condition. These improvements have …
individuals, transforming HIV infection into a chronic condition. These improvements have …
Differential signature of the microbiome and neutrophils in the oral cavity of HIV-infected individuals
HIV infection is associated with a wide range of changes in microbial communities and
immune cell components of the oral cavity. The purpose of this study was to evaluate the …
immune cell components of the oral cavity. The purpose of this study was to evaluate the …
Platelets in HIV: a guardian of host defence or transient reservoir of the virus?
E Pretorius - Frontiers in immunology, 2021 - frontiersin.org
The immune and inflammatory responses of platelets to human immunodeficiency virus 1
(HIV-1) and its envelope proteins are of great significance to both the treatment of the …
(HIV-1) and its envelope proteins are of great significance to both the treatment of the …
Alterations in circulating markers in HIV/AIDS patients with poor immune reconstitution: novel insights from microbial translocation and innate immunity
Q Xiao, F Yu, L Yan, H Zhao, F Zhang - Frontiers in Immunology, 2022 - frontiersin.org
After long-term anti-retroviral therapy (ART) treatment, most human immunodeficiency virus
(HIV)/Acquired Immure Deficiency Syndrome (AIDS) patients can achieve virological …
(HIV)/Acquired Immure Deficiency Syndrome (AIDS) patients can achieve virological …
Gr-1+ cells other than Ly6G+ neutrophils limit virus replication and promote myocardial inflammation and fibrosis following coxsackievirus B3 infection of mice
Coxsackievirus B3 (CVB3) is the primary cause of viral myocarditis. An early and abundant
neutrophil accumulation in the myocardium is a hallmark of early CVB3 infection. Yet the …
neutrophil accumulation in the myocardium is a hallmark of early CVB3 infection. Yet the …
Myeloid-derived suppressor cells and the pathogenesis of human immunodeficiency virus infection
There are several mechanisms by which human immunodeficiency virus (HIV) can mediate
immune dysfunction and exhaustion during the course of infection. Chronic immune …
immune dysfunction and exhaustion during the course of infection. Chronic immune …