Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles
Extracellular vesicles (EVs) are heterogeneous lipid containers with a complex molecular
cargo comprising several populations with unique roles in biological processes. These …
cargo comprising several populations with unique roles in biological processes. These …
Advances in the application of magnetic nanoparticles for sensing
Magnetic nanoparticles (MNPs) are of high significance in sensing as they provide viable
solutions to the enduring challenges related to lower detection limits and nonspecific effects …
solutions to the enduring challenges related to lower detection limits and nonspecific effects …
MOF positioning technology and device fabrication
Metal organic frameworks (MOFs) offer the highest surface areas per gram of any known
material. As such, they epitomise resource productivity in uses where specific surface area is …
material. As such, they epitomise resource productivity in uses where specific surface area is …
Integrated immunoisolation and protein analysis of circulating exosomes using microfluidic technology
Developing blood-based tests is appealing for non-invasive disease diagnosis, especially
when biopsy is difficult, costly, and sometimes not even an option. Tumor-derived exosomes …
when biopsy is difficult, costly, and sometimes not even an option. Tumor-derived exosomes …
Single‐molecule sensors: challenges and opportunities for quantitative analysis
JJ Gooding, K Gaus - Angewandte Chemie International …, 2016 - Wiley Online Library
Measurement science has been converging to smaller and smaller samples, such that it is
now possible to detect single molecules. This Review focuses on the next generation of …
now possible to detect single molecules. This Review focuses on the next generation of …
Advances in digital polymerase chain reaction (dPCR) and its emerging biomedical applications
Since the invention of polymerase chain reaction (PCR) in 1985, PCR has played a
significant role in molecular diagnostics for genetic diseases, pathogens, oncogenes and …
significant role in molecular diagnostics for genetic diseases, pathogens, oncogenes and …
Ultrasensitive detection of attomolar protein concentrations by dropcast single molecule assays
Measurements of very low levels of biomolecules, including proteins and nucleic acids,
remain a critical challenge in many clinical diagnostic applications due to insufficient …
remain a critical challenge in many clinical diagnostic applications due to insufficient …
Microfluidic approaches for isolation, detection, and characterization of extracellular vesicles: Current status and future directions
Extracellular vesicles (EVs) are cell-derived vesicles present in body fluids that play an
essential role in various cellular processes, such as intercellular communication …
essential role in various cellular processes, such as intercellular communication …
Nanotechnology-assisted microfluidic systems for chemical sensing, biosensing, and bioanalysis
Z Fattahi, M Hasanzadeh - TrAC Trends in Analytical Chemistry, 2022 - Elsevier
Microfluidics technology holds a special place in the field of biomedical and analytical
chemistry thanks to its properties, such as low consumption of reagent, quick analysis time …
chemistry thanks to its properties, such as low consumption of reagent, quick analysis time …
Integrated lab-on-chip biosensing systems based on magnetic particle actuation–a comprehensive review
A Van Reenen, AM de Jong, JMJ den Toonder… - Lab on a Chip, 2014 - pubs.rsc.org
The demand for easy to use and cost effective medical technologies inspires scientists to
develop innovative lab-on-chip technologies for point-of-care in vitro diagnostic testing. To …
develop innovative lab-on-chip technologies for point-of-care in vitro diagnostic testing. To …