Biological activity of ionic liquids and their application in pharmaceutics and medicine

KS Egorova, EG Gordeev, VP Ananikov - Chemical reviews, 2017 - ACS Publications
Ionic liquids are remarkable chemical compounds, which find applications in many areas of
modern science. Because of their highly tunable nature and exceptional properties, ionic …

The role of ionic liquids in the pharmaceutical field: An overview of relevant applications

SN Pedro, CS R. Freire, AJD Silvestre… - International journal of …, 2020 - mdpi.com
Solubility, bioavailability, permeation, polymorphism, and stability concerns associated to
solid-state pharmaceuticals demand for effective solutions. To overcome some of these …

Ionic liquids for therapeutic and drug delivery applications

SK Zandu, H Chopra, I Singh - Current Drug Research …, 2020 - ingentaconnect.com
Background: Ionic liquids (ILs) are ionic compounds with highly tunable and remarkable
properties which make them an important candidate in multiple domains such as extraction …

Solubility, volumetric and compressibility properties of acetaminophen in some aqueous solutions of choline based deep eutectic solvents at T=(288.15 to 318.15) K

H Shekaari, MT Zafarani-Moattar… - European Journal of …, 2017 - Elsevier
Deep eutectic solvents (DESs) as a new class of green solvents have been used to
overcome the low solubility of drugs during the recent years. In this work, the effect of some …

Solubility of cefixime in aqueous mixtures of deep eutectic solvents from experimental study and modeling

F Tajmir, A Roosta - Journal of Molecular Liquids, 2020 - Elsevier
Deep eutectic solvents (DESs) as green cosolvents can be added to water for increasing the
solubility of poorly water-soluble drugs. In this study, the solubility of cefixime is studied in …

Equilibrium solubility of acetaminophen in ternary mixtures as a tool for design of concentrated parenteral medications

A Romdhani, F Martínez, DA Chiappetta… - Journal of Solution …, 2024 - Springer
The main purpose of this research was to evaluate the mass/volume percentage (% m/v)
solubility of acetaminophen (ACP) in {ethanol (EtOH)(1)+ propylene glycol (PG)(2)+ water …

Thermodynamic study and preferential solvation of sulfamerazine in acetonitrile+ methanol cosolvent mixtures at different temperatures

RE Cárdenas-Torres, CP Ortiz, WE Acree Jr… - Journal of Molecular …, 2022 - Elsevier
This paper discusses sulfamerazine (SMR) solubility in Acetonitrile (MeCN)+ Methanol
(MeOH) cosolvents at nine temperatures (278.15–318.15 K). Herein, the maximum SMR …

Solubility of sulfamethazine in the binary mixture of acetonitrile+ methanol from 278.15 to 318.15 K: Measurement, dissolution thermodynamics, preferential solvation …

CP Ortiz, RE Cardenas-Torres, F Martínez… - Molecules, 2021 - mdpi.com
Solubility of sulfamethazine (SMT) in acetonitrile (MeCN)+ methanol (MeOH) cosolvents was
determined at nine temperatures between 278.15 and 318.15 K. From the solubility data …

Influence of 1-butyl-3-methyl imidazolium bromide, ionic liquid as co-solvent on aqueous solubility of acetaminophen

A Mehrdad, AH Miri - Journal of Molecular Liquids, 2016 - Elsevier
In this work, influence of 1-butyl-3-methyl imidazolium bromide, ionic liquid on the aqueous
solubility of acetaminophen was investigated at different temperatures and mass fraction of …

Advances brought by hydrophilic ionic liquids in fields involving pharmaceuticals

TBV Dinis, FA e Silva, F Sousa, MG Freire - Materials, 2021 - mdpi.com
The negligible volatility and high tunable nature of ionic liquids (ILs) have been the main
drivers of their investigation in a wide diversity of fields, among which is their application in …