There is a great interest to develop co-amorphous drug delivery systems to enhance the
solubility of biopharmaceutics classification system (BCS) class II and IV drugs. However …

Transglycosylation has been used to modify the physicochemical properties of original
compounds. As a result, transglycosylated compounds can form molecular aggregates in …

Our main aim in the present investigation, preparation of a drug-drug coamorphous system
(CAM) of Apremilast (APR) and Indomethacin (INDO) to improve physiochemical properties …

Differential scanning calorimetry and Raman spectroscopy were used to study the
nonisothermal and isothermal crystallization behavior of amorphous indomethacin powders …

Curcumin (CUR) is a polyphenol with a broad range of biological activity. However, CUR
possesses low solubility and short half-life, which largely affects its bioavailability. The …

Pyrazinamide (PZA) is one of the first-line drugs used in the multi-drug regimen treatment for
tuberculosis (TB). Hepatotoxicity and liver damage was found to be the major adverse event …

Co-amorphous (CM) is a promising technology for enhancing the aqueous solubility of
insoluble drugs, but the gelation phenomenon has often occurred during the dissolution …

Study aimed to design and development of a supramolecular formulation of sulpiride (SUL)
to enhance its solubility, dissolution and permeability by targeting a novel GlyT1 inhibition …

无定形固体分散体是提高难溶性药物生物利用度最有效的策略之一, 但其易受到处方因素,
制备工艺, 存储条件和溶出条件等因素的影响从而在储存期或溶出过程中结晶, 丧失溶出优势 …

Nutraceuticals is the term derived from “nutrition” and “pharmaceuticals,” thus, having
nutritional, as well as medicinal importance, with therapeutic efficacy. Nutraceuticals are …