Normal cells explore multiple states to survive stresses encountered during development
and self-renewal as well as environmental stresses such as starvation, DNA damage, toxins …

Brain metastases from breast cancer (BCBM) constitute the second most common cause of
brain metastasis (BM), and the incidence of these frequently lethal lesions is currently …

Brain metastasis, which commonly arises in patients with lung cancer, breast cancer and
melanoma, is associated with poor survival outcomes and poses distinct clinical challenges …

Breast cancer is a heterogeneous disease, and stratification of tumors is paramount to
achieve better clinical outcomes. While it is common to stratify and treat breast tumors as a …

Results A total of 243,896 patients, including 226,451 cases in control groups were
identified. Bone metastasis was found in 8848 cases, compared with 1,000 brain metastasis …

Metastasis, involving the spread of systemic cancer to the brain, results in neurologic
disability and death. Current treatments are largely palliative in nature; improved therapeutic …

The molecular events and transcriptional plasticity driving brain metastasis in clinically
relevant breast tumor subtypes has not been determined. Here we comprehensively dissect …

Breast cancer is the most commonly occurring cancer in women. There were over two-
million new cases in world in 2018. It is the second leading cause of death from cancer in …

Brain metastases (BMs) are an important source of morbidity and mortality in patients with
metastatic breast cancer (BC). As survival of patients with advanced BC considerably …

Abstract Background Brain metastases (BrM) incidence is 25% to 50% in women with
advanced human epidermal growth factor receptor 2 (HER2)‐positive breast cancer …