Carcinogenesis is accompanied by widespread DNA methylation changes within the cell.
These changes are characterized by a globally hypomethylated genome with focal …

Molecular markers, due to their stability, cost-effectiveness and ease of use provide an
immensely popular tool for a variety of applications including genome mapping, gene …

Key message Altered starch quality with full knockout of GBSS gene function in potato was
achieved using CRISPR-Cas9 technology, through transient transfection and regeneration …

An enduring question in evolutionary biology concerns the degree to which episodes of
convergent trait evolution depend on the same genetic programs, particularly over long …

The fruits of diploid and octoploid strawberry (Fragaria spp) show substantial natural
variation in color due to distinct anthocyanin accumulation and distribution patterns …

Precise genome-editing relies on the repair of sequence-specific nuclease-induced DNA
nicking or double-strand breaks (DSBs) by homology-directed repair (HDR). However …

By exome sequencing, we found de novo SMARCB1 mutations in two of five individuals with
typical Coffin-Siris syndrome (CSS), a rare autosomal dominant anomaly syndrome. As …

The world's seafood supply and trade have increased in the last decades, as well as the
potential for marketed species substitution. Currently, seafood safety and authenticity …

DNA barcoding has been widely used for herb identification in recent decades, enabling
safety and innovation in the field of herbal medicine. In this article, we summarize recent …

The primary clinical manifestations of paroxysmal nocturnal hemoglobinuria (PNH) are
hemolytic anemia, marrow failure, and thrombophilia. However, PNH is not a simple binary …