Spondyloarthritis

M Dougados, D Baeten - The Lancet, 2011 - thelancet.com
Spondyloarthritis is a group of several related but phenotypically distinct disorders: psoriatic
arthritis, arthritis related to inflammatory bowel disease, reactive arthritis, a subgroup of …

Autoimmune diseases

A Davidson, B Diamond - New England Journal of Medicine, 2001 - Mass Medical Soc
Autoimmune diseases, with the exception of rheumatoid arthritis and autoimmune thyroiditis,
are individually rare, but together they affect approximately 5 percent of the population in …

Measures of symptoms and disease status in ankylosing spondylitis: ankylosing spondylitis disease activity score (ASDAS), ankylosing spondylitis quality of life scale …

J Zochling - Arthritis care & research, 2011 - Wiley Online Library
Purpose. To measure disease activity in ankylosing spondylitis (AS) based on a composite
score of domains relevant to patients and clinicians, including both selfreported items and …

Inferences, questions and possibilities in Toll-like receptor signalling

B Beutler - Nature, 2004 - nature.com
Abstract The Toll-like receptors (TLRs) are the key proteins that allow mammals—whether
immunologically naive or experienced—to detect microbes. They lie at the core of our …

Treatment of active ankylosing spondylitis with infliximab: a randomised controlled multicentre trial

J Braun, J Brandt, J Listing, A Zink, R Alten, W Golder… - The Lancet, 2002 - thelancet.com
Background Treatment options for patients with ankylosing spondylitis are few. We aimed to
assess the effectiveness of infliximab, an antibody to tumour necrosis factor (TNF)-α, in …

Nonsteroidal antiinflammatory drugs reduce radiographic progression in patients with ankylosing spondylitis: a randomized clinical trial

A Wanders, D Heijde, R Landewé… - Arthritis & …, 2005 - Wiley Online Library
Objective A 2‐year randomized controlled trial was performed to test the hypothesis that
long‐term, continuous treatment with nonsteroidal antiinflammatory drugs (NSAIDs), in …

Efficacy and safety of infliximab in patients with ankylosing spondylitis: results of a randomized, placebo‐controlled trial (ASSERT)

D van der Heijde, B Dijkmans… - … : Official Journal of …, 2005 - Wiley Online Library
Objective The signs and symptoms of ankylosing spondylitis (AS) respond inadequately to
nonsteroidal antiinflammatory drugs, corticosteroids, and disease‐modifying antirheumatic …

RANK-L and RANK: T cells, bone loss, and mammalian evolution

LE Theill, WJ Boyle, JM Penninger - Annual review of …, 2002 - annualreviews.org
TNF and TNFR family proteins play important roles in the control of cell death, proliferation,
autoimmunity, the function of immune cells, or the organogenesis of lymphoid organs …

Development of anti-TNF therapy for rheumatoid arthritis

M Feldmann - Nature Reviews Immunology, 2002 - nature.com
The aetiology of systemic, autoimmune, chronic inflammatory diseases—such as
rheumatoid arthritis—is not known, and their pathogenesis is complex and multifactorial …

Ultrasonography of entheseal insertions in the lower limb in spondyloarthropathy

PV Balint, D Kane, H Wilson, IB McInnes… - Annals of the rheumatic …, 2002 - ard.bmj.com
Objective: To compare ultrasonography (US) with clinical examination in the detection of
entheseal abnormality of the lower limb in patients with spondyloarthropathy (SpA) …