Pattern recognition receptors (PRRs) and inflammasomes are a key part of the anti-viral
innate immune system as they detect conserved viral pathogen-associated molecular …

Molluscum contagiosum (MC) is a self-limited infectious dermatosis, frequent in pediatric
population, sexually active adults, and immunocompromised individuals. It is caused by …

Highlights•Viruses are sensed by host pattern recognition receptors during infection.•Viruses
must inhibit the innate antiviral immune response for full replication.•Viruses can sequester …

The Mpox virus (MPXV) is the causative agent of human Mpox disease–a debilitating rash
illness similar to smallpox. Although Clade I MPXV has remained endemic to West and …

The nuclear factor κB (NF-κB) family are the master transcription factors that control cell
proliferation, apoptosis, the expression of interferons and proinflammatory factors, and viral …

Nuclear factor-κB (NF-κB) is an important transcription factor that induces the expression of
antiviral genes and viral genes. NF-κB activation needs the activation of NF-κB upstream …

Monkeypox virus (MPXV), belonging to the Poxviridae family and Orthopoxvirus genus, is
closely related to the smallpox virus. Initial prodromal symptoms typically include headache …

Innate sensing of viruses by cytosolic nucleic acid sensors is a key feature of anti-viral
immunity against these pathogens. The DNA sensing pathway through the sensor cyclic …

Osteoarthritis (OA), the most prevalent form of arthritis that results from breakdown of joint
cartilage and underlying bone, has been viewed as a chronic condition manifested by …

Nuclear factor κB (NF-κB) is a family of critical transcription factors that play a critical role in
innate immune responses and inflammation, yet the molecular mechanisms responsible for …