It is an urgent need that defect repair can develop from simple device fixation to living tissue
reconstruction, from short life function replacement to permanent regeneration repair. At …

Annually, millions of patients suffer from irreversible injury owing to the loss or failure of an
organ or tissue caused by accident, aging, or disease. The combination of injectable …

Stem cells exist as normal cells in embryonic and adult tissues. In recent years, scientists
have spared efforts to determine the role of stem cells in treating many diseases. Stem cells …

Mesenchymal stromal/stem cells (MSCs) are multipotent adult stem cells that support
homeostasis during tissue regeneration. In the last decade, cell therapies based on the use …

Human pulp stem cells (PSCs) include dental pulp stem cells (DPSCs) isolated from dental
pulp tissues of human extracted permanent teeth and stem cells from human exfoliated …

The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

Craniofacial deformities (CFDs) develop following oncological resection, trauma, or
congenital disorders. Trauma is one of the top five causes of death globally, with rates …

Cells respond to and actively remodel the extracellular matrix (ECM). The dynamic and
bidirectional interaction between cells and ECM, especially their mechanical interactions …

Dental problems including cavities, periodontitis, apical periodontitis, and pulpitis are among
the most cost-consuming burden for both patients and the health care system all over the …

Introduction Human adult dental pulp stem cells (hDPSC) and stem cells from human
exfoliated deciduous teeth (SHED) hold promise in bone regeneration for their easy …