The endothelium exerts multiple actions involving regulation of vascular permeability and
tone, coagulation and fibrinolysis, inflammatory and immunological reactions and cell …

To cite this article: Maurer M, Bader M, Bas M, Bossi F, Cicardi M, Cugno M, Howarth P,
Kaplan A, Kojda G, Leeb‐Lundberg F, Lötvall J, Magerl M. New topics in bradykinin …

Angiotensin-converting enzyme 2 (ACE2) is a terminal carboxypeptidase with important
functions in the renin-angiotensin system and plays a critical role in inflammatory lung …

Kinins are vasoactive peptides that play important roles in cardiovascular homeostasis, pain
and inflammation. After release from their precursor kininogens, kinins or their C-terminal …

Background and Purpose—Brain edema is detrimental in ischemic stroke and its treatment
options are limited. Kinins are proinflammatory peptides that are released during tissue …

Introduction: Kinins are peptide mediators exerting their pro-inflammatory actions by the
selective stimulation of two distinct G-protein coupled receptors, termed BKB1R and BKB2R …

An insertion polymorphism of the angiotensin-I converting enzyme gene (ACE) is common in
humans and the higher expressing allele is associated with an increased risk of diabetic …

Activated protein C (APC) reduces mortality in severe sepsis patients and exhibits beneficial
effects in multiple animal injury models. APC anticoagulant activity involves inactivation of …

Accumulating evidence has highlighted the importance of the KKS as a protective system
against oxidative stress and organ damage in the heart and kidney. The activation of the …

OBJECTIVE Diabetic cardiomyopathy is associated with increased mortality in patients with
diabetes. The underlying pathology of this disease is still under discussion. We studied the …