The resistance mechanisms of bacteria against ciprofloxacin and new approaches for enhancing the efficacy of this antibiotic

A Shariati, M Arshadi, MA Khosrojerdi… - Frontiers in public …, 2022 - frontiersin.org
For around three decades, the fluoroquinolone (FQ) antibiotic ciprofloxacin has been used
to treat a range of diseases, including chronic otorrhea, endocarditis, lower respiratory tract …

Antimicrobial resistance in Mycobacterium tuberculosis: mechanistic and evolutionary perspectives

SM Gygli, S Borrell, A Trauner… - FEMS microbiology …, 2017 - academic.oup.com
Antibiotic-resistant Mycobacterium tuberculosis strains are threatening progress in
containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically …

Evolution of drug resistance in Mycobacterium tuberculosis: a review on the molecular determinants of resistance and implications for personalized care

N Dookie, S Rambaran, N Padayatchi… - Journal of …, 2018 - academic.oup.com
Abstract Drug-resistant TB (DR-TB) remains a significant challenge in TB treatment and
control programmes worldwide. Advances in sequencing technology have significantly …

Mechanisms of quinolone action and resistance: where do we stand?

S Correia, P Poeta, M Hébraud… - Journal of medical …, 2017 - microbiologyresearch.org
Quinolone antibiotics represent one of the most important classes of anti-infective agents
and, although still clinically valuable, their use has been compromised by the increasing …

Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences

F Coll, R McNerney, MD Preston… - Genome medicine, 2015 - Springer
Mycobacterium tuberculosis drug resistance (DR) challenges effective tuberculosis disease
control. Current molecular tests examine limited numbers of mutations, and although whole …

Drug Resistance Mechanisms in Mycobacterium tuberculosis

JC Palomino, A Martin - Antibiotics, 2014 - mdpi.com
Tuberculosis (TB) is a serious public health problem worldwide. Its situation is worsened by
the presence of multidrug resistant (MDR) strains of Mycobacterium tuberculosis, the …

Mechanisms of drug resistance in Mycobacterium tuberculosis: update 2015

Y Zhang, WW Yew - … Journal of Tuberculosis and Lung Disease, 2015 - ingentaconnect.com
Drug-resistant tuberculosis (DR-TB), including multi-and extensively drug-resistant TB, is
posing a significant challenge to effective treatment and TB control worldwide. New progress …

[图书][B] Catalogue of mutations in Mycobacterium tuberculosis complex and their association with drug resistance

World Health Organization - 2023 - books.google.com
Page 1 Catalogue of mutations in Mycobacterium tuberculosis complex and their
association with drug resistance Second edition Page 2 Page 3 Catalogue of mutations in …

Evolution and transmission of drug-resistant tuberculosis in a Russian population

N Casali, V Nikolayevskyy, Y Balabanova, SR Harris… - Nature …, 2014 - nature.com
The molecular mechanisms determining the transmissibility and prevalence of drug-resistant
tuberculosis in a population were investigated through whole-genome sequencing of 1,000 …

DNA topoisomerases

NG Bush, K Evans-Roberts, A Maxwell - EcoSal Plus, 2015 - Am Soc Microbiol
DNA topoisomerases are enzymes that control the topology of DNA in all cells. There are
two types, I and II, classified according to whether they make transient single-or double …