SM Gygli, S Borrell, A Trauner… - FEMS microbiology …, 2017 - academic.oup.com
Antibiotic-resistant Mycobacterium tuberculosis strains are threatening progress in containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically …
N Dookie, S Rambaran, N Padayatchi… - Journal of …, 2018 - academic.oup.com
Abstract Drug-resistant TB (DR-TB) remains a significant challenge in TB treatment and control programmes worldwide. Advances in sequencing technology have significantly …
Quinolone antibiotics represent one of the most important classes of anti-infective agents and, although still clinically valuable, their use has been compromised by the increasing …
F Coll, R McNerney, MD Preston… - Genome medicine, 2015 - Springer
Mycobacterium tuberculosis drug resistance (DR) challenges effective tuberculosis disease control. Current molecular tests examine limited numbers of mutations, and although whole …
JC Palomino, A Martin - Antibiotics, 2014 - mdpi.com
Tuberculosis (TB) is a serious public health problem worldwide. Its situation is worsened by the presence of multidrug resistant (MDR) strains of Mycobacterium tuberculosis, the …
Y Zhang, WW Yew - … Journal of Tuberculosis and Lung Disease, 2015 - ingentaconnect.com
Drug-resistant tuberculosis (DR-TB), including multi-and extensively drug-resistant TB, is posing a significant challenge to effective treatment and TB control worldwide. New progress …
World Health Organization - 2023 - books.google.com
Page 1 Catalogue of mutations in Mycobacterium tuberculosis complex and their association with drug resistance Second edition Page 2 Page 3 Catalogue of mutations in …
The molecular mechanisms determining the transmissibility and prevalence of drug-resistant tuberculosis in a population were investigated through whole-genome sequencing of 1,000 …
NG Bush, K Evans-Roberts, A Maxwell - EcoSal Plus, 2015 - Am Soc Microbiol
DNA topoisomerases are enzymes that control the topology of DNA in all cells. There are two types, I and II, classified according to whether they make transient single-or double …