Genetic landscape and biomarkers of hepatocellular carcinoma

J Zucman-Rossi, A Villanueva, JC Nault, JM Llovet - Gastroenterology, 2015 - Elsevier
Hepatocellular carcinoma (HCC) has emerged as a major cause of cancer-related death. Its
mortality has increased in Western populations, with a minority of patients diagnosed at …

[HTML][HTML] Targeting Wnt/β-catenin pathway in hepatocellular carcinoma treatment

V Vilchez, L Turcios, F Marti… - World journal of …, 2016 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related death
worldwide. Liver cancer is generally related to hepatitis B or C infection and cirrhosis …

Hepatocellular carcinoma and microRNA: new perspectives on therapeutics and diagnostics

N Yang, NR Ekanem, CA Sakyi, SD Ray - Advanced drug delivery reviews, 2015 - Elsevier
Hepatocellular carcinoma (HCC) remains one of the most lethal forms of cancer in the world.
In this arena, utilities of microRNA (miRNA) as a sophisticated tool, in therapeutics and …

Pregnancy-associated miRNA-clusters

DM Morales-Prieto, S Ospina-Prieto… - Journal of reproductive …, 2013 - Elsevier
MicroRNAs (miRNAs) are expressed in the placenta and can be detected in maternal
plasma. An increasing number of studies have been published on the cellular origin …

The prediction of gestational hypertension, preeclampsia and fetal growth restriction via the first trimester screening of plasma exosomal C19MC microRNAs

I Hromadnikova, L Dvorakova, K Kotlabova… - International journal of …, 2019 - mdpi.com
The aim of the study was to verify if quantification of placental specific C19MC microRNAs in
plasma exosomes would be able to differentiate during the early stages of gestation …

Obesity-associated mechanisms of hepatocarcinogenesis

R Karagozian, Z Derdák, G Baffy - Metabolism, 2014 - Elsevier
Obesity has been recognized as a key component of the metabolic syndrome, a cluster of
risk factors associated with diabetes and cardiovascular morbidity. In addition, obesity has …

ETMR: a tumor entity in its infancy

S Lambo, K von Hoff, A Korshunov, SM Pfister… - Acta …, 2020 - Springer
Abstract Embryonal tumor with Multilayered Rosettes (ETMR) is a relatively rare but typically
deadly type of brain tumor that occurs mostly in infants. Since the discovery of the …

[HTML][HTML] The emerging role of super enhancer-derived noncoding RNAs in human cancer

Y Wang, H Nie, X He, Z Liao, Y Zhou, J Zhou, C Ou - Theranostics, 2020 - ncbi.nlm.nih.gov
Super enhancers (SEs) are large clusters of adjacent enhancers that drive the expression of
genes which regulate cellular identity; SE regions can be enriched with a high density of …

MicroRNA-423-5p promotes autophagy in cancer cells and is increased in serum from hepatocarcinoma patients treated with sorafenib

P Stiuso, N Potenza, A Lombardi, I Ferrandino… - … Therapy-Nucleic Acids, 2015 - cell.com
Hepatocellular carcinoma (HCC) is the third cause of cancer-related deaths worldwide.
Sorafenib is the only approved drug for patients with advanced HCC but has shown limited …

C19MC microRNAs regulate the migration of human trophoblasts

L Xie, JF Mouillet, T Chu, WT Parks, E Sadovsky… - …, 2014 - academic.oup.com
Early in pregnancy, trophoblast invasion into the decidua and inner myometrium is essential
for establishment of proper implantation, maternal-fetal exchange, and immunological …