The COVID-19 pandemic has given the study of virus evolution and ecology new relevance.
Although viruses were first identified more than a century ago, we likely know less about …

RNA-based therapies, including RNA molecules as drugs and RNA-targeted small
molecules, offer unique opportunities to expand the range of therapeutic targets. Various …

The prediction of RNA three‐dimensional structures remains an unsolved problem. Here, we
report assessments of RNA structure predictions in CASP15, the first CASP exercise that …

Although arthropods are important viral vectors, the biodiversity of arthropod viruses, as well
as the role that arthropods have played in viral origins and evolution, is unclear. Through …

Nucleic acids are excellent at recognizing complementary sequences through the formation
of Watson− Crick base pairs. Since the base pairing enables the highly selective …

Hepatitis delta virus (HDV) is a defective virus and a satellite of the hepatitis B virus (HBV).
Its RNA genome is unique among animal viruses, but it shares common features with some …

The global burden of hepatitis B virus (HBV) is enormous, with 257 million persons
chronically infected, resulting in more than 880,000 deaths per year worldwide. HBV exists …

Hepatitis delta virus (HDV) is a small, defective RNA virus that can infect only individuals
who have hepatitis B virus (HBV); worldwide more than 15 million people are co-infected …

Ribozymes are noncoding RNAs that promote chemical transformations with rate
enhancements approaching those of protein enzymes. Although ribozymes are likely to …

Although various functions of RNA are carried out in conjunction with proteins, some
catalytic RNAs, or ribozymes, which contribute to a range of cellular processes, require little …