The diverse biological activity of recently synthesized nitro compounds

S Noriega, J Cardoso-Ortiz, A López-Luna… - Pharmaceuticals, 2022 - mdpi.com
The search for new and efficient pharmaceuticals is a constant struggle for medicinal
chemists. New substances are needed in order to treat different pathologies affecting the …

Organometallic N‐acylhydrazones of 5‐nitrofuran and 5‐nitrothiophene based: Synthesis, electrochemical, antiparasitic evaluation, and computational study

M Saldías, A Acuña, M Mellado… - Applied …, 2023 - Wiley Online Library
In searching for new therapeutic agents for treating American trypanosomiasis and Human
African trypanosomiasis, four nitroheterocyclic acylhydrazones of general formulae [R1‐CH …

Evaluation of trypanocidal properties of ferrocenyl and cyrhetrenyl N-acylhydrazones with pendant 5-nitrofuryl group

PM Toro, F Peralta, J Oyarzo, SR Wilkinson… - Journal of Inorganic …, 2021 - Elsevier
Four N-acylhydrazones of general formulae [R 1-C (O)-NH-N= C (R 2)(5-nitrofuryl)] with (R
1= ferrocenyl or cyrhetrenyl and R 2= H or Me) are synthesized and characterized in solution …

Bioorganometallic derivatives of 4-hydrazino-benzenesulphonamide as carbonic anhydrase inhibitors: Synthesis, characterisation and biological evaluation

J Brichet, R Arancibia, E Berrino… - Journal of Enzyme …, 2020 - Taylor & Francis
A series of bio-organometallic-hydrazones of the general formula [{(η5-C5H4)-C (R)= N–N
(H)-C6H4-4-SO2NH2}] MLn (MLn= Re (CO) 3, Mn (CO) 3, FeCp; R= H, CH3) were prepared …

Comparison of chemical and biological properties of organometallic complexes containing 4-and 5-nitrothienyl groups

PM Toro, J Oyarzo, R Arancibia, S Wilkinson, V Artigas… - Polyhedron, 2021 - Elsevier
This study compares the nitro group position of thienyl imines bound to organometallic
fragments, and the respective electrochemical and anti-parasitic properties. Ferrocenyl and …

Synthesis, structural characterization and antitrypanosomal activity of ferrocenyl-based imines with (2 or 4)-nitrophenyl-2-furan group

A Lucero, P Levín, D Villaman, R Arancibia… - Inorganic Chemistry …, 2024 - Elsevier
Two new metallocene complexes with formulation [Fe (η 5-C 5 H 5){(η 5-C 5 H 4)-Ndouble
bondCH-2-C 4 H 2 O-(5-C 6 H 4-2-NO 2)}](3) and [Fe (η 5-C 5 H 5){(η 5-C 5 H 4)-Ndouble …

Various Techniques for the Synthesis of 2-Nitrophenylamino-1, 4-naphthoquinone Derivatives

E Leyva, SE Loredo-Carrillo, J Aguilar - Reactions, 2023 - mdpi.com
Nitrated products are important since they are intermediates in the synthesis of other
compounds, such as explosives, perfumes, dyes and plastics, among others, and they have …

Evaluation of cyrhetrenyl and ferrocenyl precursors as 5-lipoxygenase inhibitors–biological and computational studies

M Muñoz-Osses, J Quiroz… - New Journal of …, 2021 - pubs.rsc.org
A series of ferrocenyl and cyrhetrenyl complexes [(η5-C5H4R) MLn](MLn=[(η5-C5H5Fe)(1);
MLn= Re (CO) 3 (2)) with R= H (1a; 2a), R= aldehyde (1b; 2b), R= carboxylic acid (1c; 2c) …

[HTML][HTML] Electrochemical, ESR, theoretical studies and in vitro anti-T. cruzi activity of 2-organometallic-5-nitro-benzimidazoles

G Barriga-González, C Olivares-Petit… - Journal of the Chilean …, 2020 - SciELO Chile
ABSTRACT The bioorganometallic compounds 2-cyrhetrenyl-5-nitro-benzimidazole (Bzn-1)
and 2-ferrocenyl-5-nitro-benzimidazole (Bzn-2) have been proposed as potential anti …

N-(2,2-Diphenylethyl)-4-nitrobenzamide

D Dimitrova, S Manolov, I Ivanov, D Bojilov… - Molbank, 2024 - mdpi.com
In this study, we outline the eco-friendly mechanosynthesis of N-(2, 2-diphenylethyl)-4-
nitrobenzamide by reacting 2, 2-diphenylethan-1-amine with 4-nitrobenzoyl chloride. The …