Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins
T Herdegen, JD Leah - Brain research reviews, 1998 - Elsevier
This article reviews findings up to the end of 1997 about the inducible transcription factors
(ITFs) c-Jun, JunB, JunD, c-Fos, FosB, Fra-1, Fra-2, Krox-20 (Egr-2) and Krox-24 (NGFI-A …
(ITFs) c-Jun, JunB, JunD, c-Fos, FosB, Fra-1, Fra-2, Krox-20 (Egr-2) and Krox-24 (NGFI-A …
Early growth response protein 1 (Egr-1): prototype of a zinc-finger family of transcription factors
A Gashler, VP Sukhatme - Progress in nucleic acid research and molecular …, 1995 - Elsevier
Publisher Summary This chapter discusses the early growth response protein (Egr) gene
family and its most extensively characterized member, Egr-1, first identified as an immediate …
family and its most extensively characterized member, Egr-1, first identified as an immediate …
Nuclear RNA-seq of single neurons reveals molecular signatures of activation
Single-cell sequencing methods have emerged as powerful tools for identification of
heterogeneous cell types within defined brain regions. Application of single-cell techniques …
heterogeneous cell types within defined brain regions. Application of single-cell techniques …
The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells, and oligodendrocytes
MM Daston, H Scrable, M Nordlund, AK Sturbaum… - Neuron, 1992 - Elsevier
Abstract von Recklinghausen's neurofibromatosis (NF1) is a common inherited human
disease. The events leading to patient symptoms from inheritance of a defective NF1 gene …
disease. The events leading to patient symptoms from inheritance of a defective NF1 gene …
A ligand-dependent bipartite nuclear targeting signal in the human androgen receptor. Requirement for the DNA-binding domain and modulation by NH2-terminal and …
ZX Zhou, M Sar, JA Simental, MV Lane… - Journal of Biological …, 1994 - ASBMB
The amino acid sequence requirements for androgen-dependent androgen receptor nuclear
import were determined by immunostaining transiently expressed full-length wild type and …
import were determined by immunostaining transiently expressed full-length wild type and …
Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide
U Dendorfer, P Oettgen… - Molecular and cellular …, 1994 - Am Soc Microbiol
Abstract Induction of interleukin-6 (IL-6) gene expression is mediated by numerous agents
involving all major signal transduction pathways. We have compared the effects of …
involving all major signal transduction pathways. We have compared the effects of …
Regulation of protein transport to the nucleus: central role of phosphorylation
DA Jans, S Hubner - Physiological reviews, 1996 - journals.physiology.org
Nuclear protein transport is integral to eukaryotic cell processes such as differentiation,
transformation, and the control of gene expression. Although the targeting role of nuclear …
transformation, and the control of gene expression. Although the targeting role of nuclear …
Aberrant subcellular localization of BRCA1 in breast cancer
The BRCA1 gene product was identified as a 220-kilodalton nuclear phosphoprotein in
normal cells, including breast ductal epithelial cells, and in 18 of 20 tumor cell lines derived …
normal cells, including breast ductal epithelial cells, and in 18 of 20 tumor cell lines derived …
Nuclear localization signals overlap DNA-or RNA-binding domains in nucleic acid-binding proteins.
EC LaCasse, YA Lefebvre - Nucleic acids research, 1995 - ncbi.nlm.nih.gov
Many proteins are composed of modular domains with each domain being derived froma
sequence of amino acid residues that forms a distinctive structure. Moreover, many of the …
sequence of amino acid residues that forms a distinctive structure. Moreover, many of the …
Ubiquitin-independent degradation of proteins by the proteasome
I Jariel-Encontre, G Bossis, M Piechaczyk - Biochimica et Biophysica Acta …, 2008 - Elsevier
The proteasome is the main proteolytic machinery of the cell and constitutes a recognized
drugable target, in particular for treating cancer. It is involved in the elimination of misfolded …
drugable target, in particular for treating cancer. It is involved in the elimination of misfolded …