The study of immunoglobulin genes in non-mouse and non-human models has shown that
different vertebrate groups have evolved distinct methods of generating antibody diversity …

In this review, we explain why and how rabbit monoclonal antibodies have become
outstanding reagents for laboratory research and increasingly for diagnostic and therapeutic …

Abstract The Kabat Database was initially started in 1970 to determine the combining site of
antibodies based on the available amino acid sequences at that time. Bence Jones proteins …

Antibodies of jawed-vertebrates are composed of paired heavy (H) and light (L) polypeptide
chains. Surprisingly, the sera of camelids, nurse shark and wobbegong shark, and possibly …

The rabbit immune repertoire has long been a rich source of diagnostic polyclonal
antibodies. Now it also holds great promise as a source of therapeutic monoclonal …

The antibody repertoire of rabbits has interested immunologists for decades, in part because
of the ease with which large quantities of high affinity antibodies can be obtained in serum …

Examination of 1269 unique naive chicken VH sequences showed that the majority of
positions in the framework (FW) regions were maintained as germline, with high mutation …

Rabbits have been used extensively as a model system for the elucidation of the mechanism
of immunoglobulin diversification and for the production of antibodies. We employed Next …

Rabbits generate their antibody repertoire in three stages. First, a neonatal repertoire is
generated by B lymphopoiesis in fetal liver and bone marrow and is limited by preferential …

We have developed a robust platform to generate and functionally characterize rabbit-
derived antibodies using B cells from peripheral blood. The rapid high throughput procedure …