Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): a systemic infection

A Synowiec, A Szczepański… - Clinical microbiology …, 2021 - Am Soc Microbiol
To date, seven identified coronaviruses (CoVs) have been found to infect humans; of these,
three highly pathogenic variants have emerged in the 21st century. The newest member of …

Recent discovery and development of inhibitors targeting coronaviruses

T Pillaiyar, S Meenakshisundaram, M Manickam - Drug discovery today, 2020 - Elsevier
Human coronaviruses (CoVs) are enveloped viruses with a positive-sense single-stranded
RNA genome. Currently, six human CoVs have been reported including human coronavirus …

SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosis

A Bayati, R Kumar, V Francis, PS McPherson - Journal of Biological …, 2021 - ASBMB
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
COVID-19, so understanding its biology and infection mechanisms is critical to facing this …

Structural insights into coronavirus entry

MA Tortorici, D Veesler - Advances in virus research, 2019 - Elsevier
Coronaviruses (CoVs) have caused outbreaks of deadly pneumonia in humans since the
beginning of the 21st century. The severe acute respiratory syndrome coronavirus (SARS …

Structural basis for human coronavirus attachment to sialic acid receptors

MA Tortorici, AC Walls, Y Lang, C Wang, Z Li… - Nature structural & …, 2019 - nature.com
Coronaviruses cause respiratory tract infections in humans and outbreaks of deadly
pneumonia worldwide. Infections are initiated by the transmembrane spike (S) glycoprotein …

Mechanism of baricitinib supports artificial intelligence‐predicted testing in COVID‐19 patients

J Stebbing, V Krishnan, S de Bono… - EMBO molecular …, 2020 - embopress.org
Baricitinib is an oral Janus kinase (JAK) 1/JAK 2 inhibitor approved for the treatment of
rheumatoid arthritis (RA) that was independently predicted, using artificial intelligence (AI) …

An overview on the seven pathogenic human coronaviruses

MM Kesheh, P Hosseini, S Soltani… - Reviews in Medical …, 2022 - Wiley Online Library
To date, seven human coronaviruses (HCoVs) have been detected: HCoV‐NL63, HCoV‐
229E, HCoV‐HKU1, HCoV‐OC43, severe acute respiratory syndrome coronavirus (SARS …

The extracellular matrix in skin inflammation and infection

K Pfisterer, LE Shaw, D Symmank… - Frontiers in cell and …, 2021 - frontiersin.org
The extracellular matrix (ECM) is an integral component of all organs and plays a pivotal
role in tissue homeostasis and repair. While the ECM was long thought to mostly have …

The role of extracellular vesicles in COVID-19 virus infection

M Hassanpour, J Rezaie, M Nouri, Y Panahi - Infection, Genetics and …, 2020 - Elsevier
Extracellular vesicles releasing from various types of cells contribute to intercellular
communication via delivering bio-molecules like nucleic acids, proteins, and lipids to …

An imidazolium-based zwitterionic polymer for antiviral and antibacterial dual functional coatings

P Chen, J Lang, Y Zhou, A Khlyustova, Z Zhang… - Science …, 2022 - science.org
To reduce the severe health risk and the huge economic impact associated with the fomite
transmission of SARS-CoV-2, an imidazolium-based zwitterionic polymer was designed …