Recombination of Porcine Reproductive and Respiratory Syndrome Virus: Features, Possible Mechanisms, and Future Directions

XY Cui, DS Xia, LZ Luo, TQ An - Viruses, 2024 - mdpi.com
Recombination is a pervasive phenomenon in RNA viruses and an important strategy for
accelerating the evolution of RNA virus populations. Recombination in the porcine …

Phenotypic characterization of a virulent PRRSV-1 isolate in a reproductive model with and without prior heterologous modified live PRRSV-1 vaccination

H Kreutzmann, J Stadler, C Knecht… - Frontiers in Veterinary …, 2022 - frontiersin.org
Reproductive disorders induced by porcine reproductive and respiratory syndrome virus
(PRRSV) cause high economic losses in the pig industry worldwide. In this study, we aimed …

A porcine reproductive and respiratory syndrome virus (PRRSV)-specific IgM as a novel adjuvant for an inactivated PRRSV vaccine improves protection efficiency and …

R Chen, B Liu, X Zhang, M Qin, J Dong, G Gu, C Wu… - Veterinary …, 2022 - Springer
Current strategies for porcine reproductive and respiratory syndrome (PRRS) control are
inadequate and mainly restricted to immunization using different PRRS virus (PPRSV) …

A molecular and epidemiological description of a severe porcine reproductive and respiratory syndrome outbreak in a commercial swine production system in Russia

KA Havas, DN Makau, S Shapovalov, E Tolkova… - Viruses, 2022 - mdpi.com
Porcine reproductive and respiratory syndrome (PRRS) is an economically devastating
disease of swine in many parts of the world. Porcine reproductive and respiratory syndrome …

Genome-wide mRNA and long non-coding RNA analysis of porcine trophoblast cells infected with porcine reproductive and respiratory syndrome virus associated …

X Zhang, X Liu, J Peng, S Song, G Xu, N Yang… - International Journal of …, 2023 - mdpi.com
Porcine reproductive and respiratory syndrome (PRRS) is a vertically transmitted
reproductive disorder that is typically characterized by miscarriage, premature birth, and …

Evaluation of porcine GM-CSF during PRRSV infection in vitro and in vivo indicating a protective role of GM-CSF related with M1 biased activation in alveolar …

Q Ji, G Qu, B Liu, Y Bai, G Wang, R Chen… - Frontiers in …, 2022 - frontiersin.org
Granulocyte-macrophage colony stimulating factor (GM-CSF), participates in diverse
biological processes associated with innate and adaptive immunity, has unknown effects …

Characterization of in vitro viral neutralization targets of highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) in alveolar macrophage …

B Liu, X Zheng, X Sun, B Wan, J Dong, Z Zhou… - Veterinary …, 2024 - Elsevier
Porcine reproductive and respiratory syndrome virus (PRRSV) poses a significant threat to
the global pork industry, resulting in substantial economic losses. Current control measures …

Innate Immune Evasion of PRRSV nsp11 through Degradation of the HDAC2 by Its Endoribonuclease Activity

H Zhang, J Chen, C Yu, Y Pan, W Ma, H Feng, J Xie… - Viruses, 2024 - mdpi.com
Porcine reproductive and respiratory syndrome virus (PRRSV), a member of the Arteriviridae
family, represents a persistent menace to the global pig industry, causing reproductive …

An Outbreak of a Respiratory Disorder at a Russian Swine Farm Associated with the Co-Circulation of PRRSV1 and PRRSV2

S Raev, A Yuzhakov, A Bulgakov, L Kostina… - Viruses, 2020 - mdpi.com
We conducted a cross-sectional study to identify the major respiratory pathogen responsible
for an outbreak of respiratory disease at a swine farm in West Siberia in 2019. We …

A broadly neutralizing monoclonal antibody induces broad protection against heterogeneous PRRSV strains in piglets

Z Zhang, T Zhai, M Li, K Zhang, J Li, X Zheng, C Tian… - Veterinary …, 2021 - Springer
Neutralizing antibodies (NAbs) have attracted attention as tools for achieving PRRSV control
and prevention, but viral antigenic variation undermines the abilities of NAbs elicited by …