Natural and synthetic polymers as drug carriers for delivery of therapeutic proteins

MS Hamid Akash, K Rehman, S Chen - Polymer Reviews, 2015 - Taylor & Francis
In order to cure and treat health-related disorders, therapeutic substance must reach its
target site with a constant concentration over a long period of time. As oral administration is …

Advances in natural polymers as pharmaceutical excipients

IJ Ogaji, EI Nep, JD Audu-Peter - 2012 - irepos.unijos.edu.ng
Research in natural polymeric materials has witnessed growing interest and attention. This
is attributable to a number of factors which include their relative abundance, low cost, and …

IL-1Ra and its delivery strategies: inserting the association in perspective

MSH Akash, K Rehman, S Chen - Pharmaceutical research, 2013 - Springer
Abstract Interleukin-1 receptor antagonist (IL-1Ra) is a naturally occurring anti-inflammatory
antagonist of interleukin-1 family of pro-inflammatory cytokines. The broad spectrum anti …

Development of film forming gel for the delivery of 5-flurouracil: in-vitro/ex-vivo evaluation

SN Hussain Shah, Zulcaif, A Syed, A Aslam, N Zafar… - Polymer Bulletin, 2024 - Springer
The transdermal route is an important delivery system for the delivery of both systemic and
local effects. The effectiveness of therapy is based on adherence of transdermal dosage …

Polymeric-based particulate systems for delivery of therapeutic proteins

MSH Akash, K Rehman, S Chen - … development and technology, 2016 - Taylor & Francis
Polymeric-based particulate systems have been intensively developed to increase the short
biological half-life and prevent enzymatic degradation of therapeutic proteins. These …

Delivery of therapeutic proteins: challenges and strategies

K Rehman, M Sajid Hamid Akash, B Akhtar… - Current drug …, 2016 - ingentaconnect.com
Recent advances in genetic engineering and pharmaceutical biotechnology have made
possible to combat life-threatening diseases with efficient delivery of therapeutic proteins …

Design and evaluation of lipoprotein resembling curcumin-encapsulated protein-free nanostructured lipid carrier for brain targeting

F Meng, S Asghar, Y Xu, J Wang, X Jin, Z Wang… - International Journal of …, 2016 - Elsevier
Many nanoparticle matrixes have been demonstrated to be efficient in brain targeting, but
there are still certain limitations for them. To overcome the shortcomings of the existing …

Screening of stabilizing agents to optimize flurbiprofen nanosuspensions using experimental design

AN Oktay, S Ilbasmis-Tamer, A Karakucuk… - Journal of drug delivery …, 2020 - Elsevier
Although flurbiprofen (FB), as one of non-steroidal anti-inflammatory drugs, has various
pharmacological applications, it shows low dermal bioavailability due to its low water …

Experimental and in silico evaluation of Carthamus tinctorius L. oil emulgel: a promising treatment for bacterial skin infections

J Saeed, SN Hussain Shah, H Javed… - Frontiers in Cellular …, 2023 - frontiersin.org
Purpose The current study aimed to develop a topical herbal emulgel containing Carthamus
tinctorius L.(CT) oil extract, which has been scientifically proven for its antibacterial and …

Natural gums as sustained release carriers: Development of gastroretentive drug delivery system of ziprasidone HCl

R Aj, Y Hn, S Sb - DARU Journal of Pharmaceutical Sciences, 2012 - Springer
Background Objective of this study is to show the potential use of natural gums in the
development of drug delivery systems. Therefore in this work gastro retentive tablet …