The clearance of dead cells by efferocytosis
E Boada-Romero, J Martinez, BL Heckmann… - … reviews Molecular cell …, 2020 - nature.com
Multiple modes of cell death have been identified, each with a unique function and each
induced in a setting-dependent manner. As billions of cells die during mammalian …
induced in a setting-dependent manner. As billions of cells die during mammalian …
Adhesion G protein-coupled receptors: structure, signaling, physiology, and pathophysiology
T Lala, RA Hall - Physiological Reviews, 2022 - journals.physiology.org
Adhesion G protein-coupled receptors: structure, signaling, physiology, and
pathophysiology Page 1 REVIEW ARTICLE ADHESION G PROTEIN-COUPLED …
pathophysiology Page 1 REVIEW ARTICLE ADHESION G PROTEIN-COUPLED …
G protein-coupled receptors in neurodegenerative diseases and psychiatric disorders
Neuropsychiatric disorders are multifactorial disorders with diverse aetiological factors.
Identifying treatment targets is challenging because the diseases are resulting from …
Identifying treatment targets is challenging because the diseases are resulting from …
In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation
EF Spence, S Dube, A Uezu, M Locke… - Nature …, 2019 - nature.com
Excitatory synapse formation during development involves the complex orchestration of both
structural and functional alterations at the postsynapse. However, the molecular …
structural and functional alterations at the postsynapse. However, the molecular …
Efferocytosis in the central nervous system
J Zhao, W Zhang, T Wu, H Wang, J Mao… - Frontiers in cell and …, 2021 - frontiersin.org
The effective clearance of apoptotic cells is essential for maintaining central nervous system
(CNS) homeostasis and restoring homeostasis after injury. In most cases of physiological …
(CNS) homeostasis and restoring homeostasis after injury. In most cases of physiological …
FMRP links optimal codons to mRNA stability in neurons
Fragile X syndrome (FXS) is caused by inactivation of the FMR1 gene and loss of encoded
FMRP, an RNA binding protein that represses translation of some of its target transcripts …
FMRP, an RNA binding protein that represses translation of some of its target transcripts …
Emerging roles of adhesion G protein-coupled receptors
M Rosa, T Noel, M Harris… - Biochemical Society …, 2021 - portlandpress.com
Adhesion G protein-coupled receptors (aGPCRs) form a sub-group within the GPCR
superfamily. Their distinctive structure contains an abnormally large N-terminal, extracellular …
superfamily. Their distinctive structure contains an abnormally large N-terminal, extracellular …
Mice lacking full length Adgrb1 (Bai1) exhibit social deficits, increased seizure susceptibility, and altered brain development
The adhesion G protein-coupled receptor BAI1/ADGRB1 plays an important role in
suppressing angiogenesis, mediating phagocytosis, and acting as a brain tumor suppressor …
suppressing angiogenesis, mediating phagocytosis, and acting as a brain tumor suppressor …
The adhesion-GPCR BAI1 promotes excitatory synaptogenesis by coordinating bidirectional trans-synaptic signaling
Excitatory synapses are specialized cell–cell contacts located on actin-rich dendritic spines
that mediate information flow and storage in the brain. The postsynaptic adhesion-G protein …
that mediate information flow and storage in the brain. The postsynaptic adhesion-G protein …
Prediction of G protein‐coupled receptors with SVM‐prot features and random forest
G protein‐coupled receptors (GPCRs) are the largest receptor superfamily. In this paper, we
try to employ physical‐chemical properties, which come from SVM‐Prot, to represent GPCR …
try to employ physical‐chemical properties, which come from SVM‐Prot, to represent GPCR …