[HTML][HTML] The emergence, genomic diversity and global spread of SARS-CoV-2

J Li, S Lai, GF Gao, W Shi - Nature, 2021 - nature.com
Since the first cases of COVID-19 were documented in Wuhan, China in 2019, the world has
witnessed a devastating global pandemic, with more than 238 million cases, nearly 5 million …

[HTML][HTML] Mechanisms of SARS-CoV-2 entry into cells

CB Jackson, M Farzan, B Chen, H Choe - Nature reviews Molecular …, 2022 - nature.com
The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …

[HTML][HTML] Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination events

J Ou, W Lan, X Wu, T Zhao, B Duan, P Yang… - … and Targeted Therapy, 2022 - nature.com
The current pandemic of COVID-19 is fueled by more infectious emergent Omicron variants.
Ongoing concerns of emergent variants include possible recombinants, as genome …

[HTML][HTML] SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape

TN Starr, N Czudnochowski, Z Liu, F Zatta, YJ Park… - Nature, 2021 - nature.com
An ideal therapeutic anti-SARS-CoV-2 antibody would resist viral escape,–, have activity
against diverse sarbecoviruses,,–, and be highly protective through viral neutralization,,–and …

Self‐powered respiration monitoring enabled by a triboelectric nanogenerator

Y Su, G Chen, C Chen, Q Gong, G Xie… - Advanced …, 2021 - Wiley Online Library
In mammals, physiological respiration involves respiratory cycles of inhaled and exhaled
breaths, which has traditionally been an underutilized resource potentially encompassing a …

[HTML][HTML] The next phase of SARS-CoV-2 surveillance: real-time molecular epidemiology

BB Oude Munnink, N Worp, DF Nieuwenhuijse… - Nature medicine, 2021 - nature.com
The current coronavirus disease 2019 (COVID-19) pandemic is the first to apply whole-
genome sequencing near to real time, with over 2 million severe acute respiratory syndrome …

[HTML][HTML] High genetic barrier to SARS-CoV-2 polyclonal neutralizing antibody escape

F Schmidt, Y Weisblum, M Rutkowska, D Poston… - Nature, 2021 - nature.com
The number and variability of the neutralizing epitopes targeted by polyclonal antibodies in
individuals who are SARS-CoV-2 convalescent and vaccinated are key determinants of …

[HTML][HTML] Pandemics throughout history

J Piret, G Boivin - Frontiers in microbiology, 2021 - frontiersin.org
The emergence and spread of infectious diseases with pandemic potential occurred
regularly throughout history. Major pandemics and epidemics such as plague, cholera, flu …

[HTML][HTML] Coronavirus biology and replication: implications for SARS-CoV-2

P V'kovski, A Kratzel, S Steiner, H Stalder… - Nature Reviews …, 2021 - nature.com
The SARS-CoV-2 pandemic and its unprecedented global societal and economic disruptive
impact has marked the third zoonotic introduction of a highly pathogenic coronavirus into the …

[PDF][PDF] Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations

F Muecksch, Y Weisblum, CO Barnes, F Schmidt… - Immunity, 2021 - cell.com
Antibodies elicited by infection accumulate somatic mutations in germinal centers that can
increase affinity for cognate antigens. We analyzed 6 independent groups of clonally related …