Obesity-associated biomarkers and executive function in children

AL Miller, HJ Lee, JC Lumeng - Pediatric research, 2015 - nature.com
There is a growing focus on links between obesity and cognitive decline in adulthood,
including Alzheimer's disease. It is also increasingly recognized that obesity in youth is …

Androgen regulation of the mesocorticolimbic system and executive function

DJ Tobiansky, KG Wallin-Miller, SB Floresco… - Frontiers in …, 2018 - frontiersin.org
Multiple lines of evidence indicate that androgens, such as testosterone, modulate the
mesocorticolimbic system and executive function. This review integrates neuroanatomical …

Liraglutide promotes improvements in objective measures of cognitive dysfunction in individuals with mood disorders: a pilot, open-label study

RB Mansur, J Ahmed, DS Cha… - Journal of affective …, 2017 - Elsevier
Background There is a paucity of treatments that are capable of reliably and robustly
improving cognitive function in adults with mood disorders. Glucagon-like peptide-1 is …

Liraglutide improves memory in obese patients with prediabetes or early type 2 diabetes: a randomized, controlled study

F Vadini, PG Simeone, A Boccatonda… - International Journal of …, 2020 - nature.com
Background/objectives Diabetic subjects are at increased risk of subtle cognitive impairment
since the disease early stages and of dementia later in life. In animal models, glucagon-like …

Visceral adiposity, inflammation, and hippocampal function in obesity

AM Stranahan - Neuropharmacology, 2022 - Elsevier
The 'apple-shaped'anatomical pattern that accompanies visceral adiposity increases risk for
multiple chronic diseases, including conditions that impact the brain, such as diabetes and …

Obesity weighs down memory through a mechanism involving the neuroepigenetic dysregulation of Sirt1

FD Heyward, D Gilliam, MA Coleman… - Journal of …, 2016 - Soc Neuroscience
Aberrant gene expression within the hippocampus has recently been implicated in the
pathogenesis of obesity-induced memory impairment. Whether a dysregulation of epigenetic …

A systematic review of the evidence that brain structure is related to muscle structure and their relationship to brain and muscle function in humans over the lifecourse

AHM Kilgour, OM Todd, JM Starr - BMC geriatrics, 2014 - Springer
Background An association between cognition and physical function has been shown to
exist but the roles of muscle and brain structure in this relationship are not fully understood …

Treatment with a GLP− 1R agonist over four weeks promotes weight loss-moderated changes in frontal-striatal brain structures in individuals with mood disorders

RB Mansur, A Zugman, J Ahmed, DS Cha… - European …, 2017 - Elsevier
Cognitive deficits are a core feature across psychiatric disorders. Emerging evidence
indicates that metabolic pathways are highly relevant for the substrates and phenomenology …

Association between the triglyceride-glucose index and cognitive impairment in China: a community population-based cross-sectional study

Y Ma, S Wei, L Dang, L Gao, S Shang, N Hu… - Nutritional …, 2024 - Taylor & Francis
Introduction Insulin resistance (IR) is a feature of metabolic syndrome and plays an
important role in cognitive impairment (CI). The triglyceride-glucose (TyG) index is a …

Potential factors associated with perceived cognitive impairment in breast cancer survivors

JS Myers, JA Wick, J Klemp - Supportive Care in Cancer, 2015 - Springer
Purpose This cross-sectional study was designed to explore potential factors associated
with perceived cognitive impairment (PCI) in breast cancer survivors compared to controls …