Colorectal cancer (CRC) is known as the third most common cancer as well as the fourth
most deadly cancer worldwide. CRC accounts for approximately 10% of all new cancer …

Many chemotherapeutic drugs have been used for the treatment of cancer, for instance,
doxorubicin, irinotecan, 5-fluorouracil, cisplatin, and paclitaxel. However, the effectiveness of …

5-fluorouracil (5-FU) is among the mostly administrated chemotherapeutic agents for a wide
variety of neoplasms. Non-coding RNAs have a central impact on the determination of the …

Epigenetic regulation by microRNAs (miRs) demonstrated a promising therapeutic potential
of these molecules to regulate genetic activity in different cancers, including colorectal …

Long non-coding RNAs (lncRNAs) are longer than 200 nts non-coding transcripts and have
recently emerged as one of the largest and significantly diverse RNA families whereas …

Desmosomes play a key role in the regulation of cell adhesion and signaling. Dysregulation
of the desmosome complex is associated with the loss of epithelial cell polarity and …

Colorectal cancer (CRC) is one of the most common cancers globally. Despite recent
advances in therapeutic approaches, this cancer continues to have a poor prognosis …

OncomiRNAs involved in human colorectal cancer (CRC) are capable of suppressing the
expression of their targets via cleavage or translational arrest. Therefore, an improved …

Gastrointestinal (GI) cancers, including colorectal, gastric, hepatic, esophageal, and
pancreatic tumors, are responsible for large numbers of deaths around the world …

Breast cancer (BC) formation is primarily influenced by genetics, epigenetics and
environmental factors. Aberrant Genetics and epigenetics leads to a condition known as …