Local cancer recurrence: the realities, challenges, and opportunities for new therapies

DA Mahvi, R Liu, MW Grinstaff… - CA: a cancer journal …, 2018 - Wiley Online Library
Locoregional recurrence negatively impacts both long‐term survival and quality of life for
several malignancies. For appropriate‐risk patients with an isolated, resectable, local …

Defining low anterior resection syndrome: a systematic review of the literature

C Keane, C Wells, G O'Grady, IP Bissett - Colorectal disease, 2017 - Wiley Online Library
Aim There is increasing awareness of the poor functional outcome suffered by many patients
after sphincter‐preserving rectal resection, termed 'low anterior resection syndrome'(LARS) …

The American society of colon and rectal surgeons clinical practice guidelines for the management of rectal cancer

YN You, KM Hardiman, A Bafford, V Poylin… - Diseases of the Colon …, 2020 - journals.lww.com
The American Society of Colon and Rectal Surgeons (ASCRS) is dedicated to ensuring high-
quality patient care by advancing the science, prevention, and management of disorders …

[HTML][HTML] Bowel function 14 years after preoperative short-course radiotherapy and total mesorectal excision for rectal cancer: report of a multicenter randomized trial

TYT Chen, LM Wiltink, RA Nout, EMK Kranenbarg… - Clinical colorectal …, 2015 - Elsevier
Background We investigated very long-term bowel function after total mesorectal excision
(TME) with or without preoperative short-course radiotherapy (PRT) for rectal cancer, the risk …

Cancer survivorship: an integral part of Europe's research agenda

P Lagergren, A Schandl, NK Aaronson… - Molecular …, 2019 - Wiley Online Library
Cancer survivorship has traditionally received little prioritisation and attention. For a long
time, the treatment of cancer has been the main focus of healthcare providers' efforts. It is …

Impact of long-course neoadjuvant radiation on postoperative low anterior resection syndrome and quality of life in rectal cancer: post hoc analysis of a randomized …

W Sun, R Dou, J Chen, S Lai, C Zhang, L Ruan… - Annals of surgical …, 2019 - Springer
Background Neoadjuvant radiation is recommended for locally advanced rectal cancer, with
proven benefit in local control but not in disease-free survival. However, the impact of long …

Predicting response to neoadjuvant chemoradiotherapy in rectal cancer: from biomarkers to tumor models

M Li, Q Xiao, N Venkatachalam… - Therapeutic …, 2022 - journals.sagepub.com
Colorectal cancer (CRC) is a major contributor to cancer-associated morbidity worldwide
and over one-third of CRC is located in the rectum. Neoadjuvant chemoradiotherapy (nCRT) …

Organ preservation in cT2N0 rectal cancer after neoadjuvant chemoradiation therapy: the impact of radiation therapy dose-escalation and consolidation …

A Habr-Gama, GP São Julião, BB Vailati… - Annals of …, 2019 - journals.lww.com
Objective: To demonstrate the difference in organ-preservation rates and avoidance of
definitive surgery among cT2N0 rectal cancer patients undergoing 2 different …

Long-term functional follow-up after anterior rectal resection for cancer

A Sturiale, J Martellucci, L Zurli, C Vaccaro… - International journal of …, 2017 - Springer
Purpose This is a retrospective analysis including all of the patients that have undergone
anterior resection for rectal cancer from January 1998 to December 2005 in two tertiary …

Urinary dysfunction after rectal cancer surgery: results from a randomized trial comparing mesorectal excision with and without lateral lymph node dissection for …

M Ito, A Kobayashi, S Fujita, J Mizusawa… - European Journal of …, 2018 - Elsevier
Background Postoperative urinary dysfunction is a major complication of rectal cancer
surgery. A randomized controlled trial (JCOG0212) concluded that the noninferiority of …