In Vivo Antimalarial Activity and Mechanisms of Action of 4-Nerolidylcatechol Derivatives
LF Rocha e Silva, KL Nogueira, ACS Pinto… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Nerolidylcatechol (1) is an abundant antiplasmodial metabolite that is isolated from Piper
peltatum roots. O-Acylation or O-alkylation of compound 1 provides derivatives exhibiting …
peltatum roots. O-Acylation or O-alkylation of compound 1 provides derivatives exhibiting …
Stability and antioxidant activity of semi-synthetic derivatives of 4-nerolidylcatechol
ES Lima, ACS Pinto, KL Nogueira, LFR e Silva… - Molecules, 2012 - mdpi.com
4-nerolidylcatechol (4-NC) is an unstable natural product that exhibits important antioxidant,
anti-inflammatory and other properties. It is readily obtainable on a multi-gram scale through …
anti-inflammatory and other properties. It is readily obtainable on a multi-gram scale through …
Malaria chemotherapy: recent advances in drug development
S Gemma, V Travagli, L Savini… - Recent patents on …, 2010 - ingentaconnect.com
Malaria is a disease caused by parasitic protozoa of the genus Plasmodium. Despite
significant advances in understanding the disease and the parasite biology, malaria still …
significant advances in understanding the disease and the parasite biology, malaria still …
Identificação de potenciais novos antimaláricos a partir de produtos naturais de plantas amazônicas, e seus derivados: estudos in vitro, in vivo e de mecanismo de …
LFR Silva - 2014 - tede.ufam.edu.br
RESUMO O aumento da resistência do Plasmodium spp. aos antimaláricos atualmente
disponíveis tem impulsionado a busca de novas drogas para o tratamento da malária. A …
disponíveis tem impulsionado a busca de novas drogas para o tratamento da malária. A …