Mechanical force-induced signal transduction in lung cells
The lung is a unique organ in that it is exposed to physical forces derived from breathing,
blood flow, and surface tension throughout life. Over the past decade, significant progress …
blood flow, and surface tension throughout life. Over the past decade, significant progress …
Fetal lung liquid: a major determinant of the growth and functional development of the fetal lung
During fetal life the lung develops as a liquid‐filled organ. This liquid is produced by the fetal
lung and leaves via the trachea from where it is either swallowed or enters the amniotic sac …
lung and leaves via the trachea from where it is either swallowed or enters the amniotic sac …
Correction of congenital diaphragmatic hernia in utero VIII: Response of the hypoplastic lung to tracheal occlusion
MR Harrison, NS Adzick, AW Flake… - Journal of pediatric …, 1996 - Elsevier
Most fetuses with congenital diaphragmatic hernia (CDH) diagnosed before 24 weeks'
gestation die despite optimal postnatal care. In fetuses with liver herniation into the chest …
gestation die despite optimal postnatal care. In fetuses with liver herniation into the chest …
The effects of mechanical forces on lung functions
HR Wirtz, LG Dobbs - Respiration physiology, 2000 - Elsevier
The lung is a dynamic organ that is subjected to mechanical forces throughout development
and adult life. This review article addresses the types of mechanical forces in the lung and …
and adult life. This review article addresses the types of mechanical forces in the lung and …
Cardiopulmonary changes with aeration of the newborn lung
The newborn's transition from fetal to neonatal life includes aeration of the lungs,
establishment of pulmonary gas exchange and changing the fetal circulation into the adult …
establishment of pulmonary gas exchange and changing the fetal circulation into the adult …
Developmental regulation of lung liquid transport
RE Olver, DV Walters, S M. Wilson - Annu. Rev. Physiol., 2004 - annualreviews.org
▪ Abstract The developing distal lung epithelium displays an evolving liquid transport
phenotype, reflecting a changing and dynamic balance between Cl− ion secretion and Na+ …
phenotype, reflecting a changing and dynamic balance between Cl− ion secretion and Na+ …
Spontaneous peristaltic airway contractions propel lung liquid through the bronchial tree of intact and fetal lung explants
JC Schittny, G Miserocchi… - American journal of …, 2000 - atsjournals.org
Spontaneous contractions of the fetal airways are a well recognized but poorly characterized
phenomenon. In the present study spontaneous narrowing of the airways was analyzed in …
phenomenon. In the present study spontaneous narrowing of the airways was analyzed in …
The effects of mechanical forces on fetal lung growth
JA Kitterman - Clinics in perinatology, 1996 - Elsevier
Pulmonary hypoplasia is an increasingly important cause of neonatal morbidity and
mortality. Clinical experience and studies in experimental animals indicate that growth of the …
mortality. Clinical experience and studies in experimental animals indicate that growth of the …
[HTML][HTML] Mechanobiology in lung epithelial cells: measurements, perturbations, and responses
Epithelial cells of the lung are located at the interface between the environment and the
organism and serve many important functions including barrier protection, fluid balance …
organism and serve many important functions including barrier protection, fluid balance …
Invited review: mechanochemical signal transduction in the fetal lung
Growth and maturation of fetal lungs are regulated by both humoral and physical factors.
Mechanical stretch stimulates fetal lung cell proliferation and affects fetal lung maturation by …
Mechanical stretch stimulates fetal lung cell proliferation and affects fetal lung maturation by …