Mesenchymal stem cell (MSC) is an intensely studied stem cell type applied for cardiac
repair. For decades, the preclinical researches on animal model and clinical trials have …

Introduction Ischemic heart diseases, especially the myocardial infarction, is a major hazard
problem to human health. Despite substantial advances in control of risk factors and …

Background—Phase I clinical studies have demonstrated the feasibility of implanting
autologous skeletal myoblasts in postinfarction scars. However, they have failed to …

Ventricular tachyarrhythmias (VAs) commonly occur early in ischaemia, and remain a
common cause of sudden death in acute MI. The thrombolysis and primary percutaneous …

Objectives: The aim of this study was to quantify acute myocardial retention of cardiac-
derived stem cells (CDCs) and evaluate different delivery methods with positron emission …

Rationale: The success of cardiac stem cell therapies is limited by low cell retention, due at
least in part to washout via coronary veins. Objective: We sought to counter the efflux of …

Aims Despite accumulated evidence that intracoronary bone marrow cell (BMC) therapy
may be beneficial in acute myocardial infarction, there are only limited data available on the …

The versatility of pluripotent stem cells, attributable to their unlimited self-renewal capacity
and plasticity, has sparked a considerable interest for potential application in regenerative …

Noncellular differentiation effects have emerged as important mechanisms mediating
therapeutic effects of stem or progenitor cell transplantation. Here, we investigated the …

Cardiac cell therapy has now been in clinical use since 10years. Both autologous skeletal
myoblasts and bone marrow-derived different cell subsets (mononuclear cells …