Irinotecan is a camptothecin analog used as an anticancer drug. Severe, potentially life-
threatening toxicities can occur from irinotecan treatment. Although multiple genes may play …

eHealth is an umbrella term incorporating any area that combines healthcare and
technology to improve efficiencies and reduce costs. The ultimate goal of eHealth is to …

Pharmacogenomics, driven by advances in genomics, helps to explain patients' individual
variability in response to therapies. Personalized medicine, the application of the increasing …

Personalized medicine is a multidisciplinary area that contains several techniques to
provide patients with more efficient, cheaper, and fewer side effects treatment strategies. In …

Recent advances in high-throughput gene sequencing and other omics biotechnologies
have served as a springboard for the field of pharmacogenomics. Pharmacogenomics is …

Aim: Fast and frugal decision trees (FFTs) can simplify clinical decision making by providing
a heuristic approach to contextual guidance. We wanted to use FFTs for pharmacogenomic …

Typically, chemotherapy selection takes into account patient demographic data, including
disease symptoms, family history, environmental factors and concurrent medications …

Although much work has been done over the past decade on developing personalized and
evidence-based medicine, such as diagnostic tests based on genetics to better predict …

Regulatory Considerations in Pharmacogenomics at EMA and US FDA. — PMU
Forschungsportal Zur Hauptnavigation wechseln Zur Suche wechseln Zum Hauptinhalt …