Circadian rhythms disrupted by light at night and mistimed food intake alter hormonal rhythms and metabolism

OH Meléndez-Fernández, JA Liu… - International Journal of …, 2023 - mdpi.com
Availability of artificial light and light-emitting devices have altered human temporal life,
allowing 24-hour healthcare, commerce and production, and expanding social life around …

Endocrine disrupting chemicals in polycystic ovary syndrome: the relevant role of the theca and granulosa cells in the pathogenesis of the ovarian dysfunction

M Jozkowiak, H Piotrowska-Kempisty, D Kobylarek… - Cells, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common heterogeneous endocrine disorder
among women of reproductive age. The pathogenesis of PCOS remains elusive; however …

Workload for radiologists during on-call hours: dramatic increase in the past 15 years

RJM Bruls, RM Kwee - Insights into imaging, 2020 - Springer
Background The objective of this study is to investigate the workload for radiologists during
on-call hours and to quantify the 15-year trend in a large general hospital in Western …

Epilepsy care in the time of COVID-19 pandemic in Italy: risk factors for seizure worsening

G Assenza, J Lanzone, F Brigo, A Coppola… - Frontiers in …, 2020 - frontiersin.org
Objective: In early 2020, Italy struggled with an unprecedented health emergency related to
the COVID-19 pandemic. Medical care of chronic neurological diseases, such as epilepsy, is …

Stimulation of the hepatoportal nerve plexus with focused ultrasound restores glucose homoeostasis in diabetic mice, rats and swine

V Cotero, J Graf, H Miwa, Z Hirschstein… - Nature Biomedical …, 2022 - nature.com
Peripheral neurons that sense glucose relay signals of glucose availability to integrative
clusters of neurons in the brain. However, the roles of such signalling pathways in the …

GABA and l-theanine mixture decreases sleep latency and improves NREM sleep

S Kim, K Jo, KB Hong, SH Han, HJ Suh - Pharmaceutical biology, 2019 - Taylor & Francis
Context: γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter and it is well
established that activation of GABAA receptors favours sleep. l-Theanine, a naturally …

Coupled network of the circadian clocks: a driving force of rhythmic physiology

AM Finger, C Dibner, A Kramer - FEBS letters, 2020 - Wiley Online Library
The circadian system is composed of coupled endogenous oscillators that allow living
beings, including humans, to anticipate and adapt to daily changes in their environment. In …

[HTML][HTML] Association between circadian rhythm disruption and polycystic ovary syndrome

F Wang, N Xie, Y Wu, Q Zhang, Y Zhu, M Dai, J Zhou… - Fertility and sterility, 2021 - Elsevier
Objective To explore the association of circadian rhythm disruption with polycystic ovary
syndrome (PCOS) and the potential underlying mechanism in ovarian granulosa cells …

[HTML][HTML] Current nutritional and pharmacological anti-aging interventions

M Ros, JM Carrascosa - Biochimica et Biophysica Acta (BBA)-Molecular …, 2020 - Elsevier
Aging is the main risk factor for chronic diseases and disablement in human societies with a
great impact in social and health care expenditures. So far, aging and, eventually, death are …

G1/S cell cycle regulators mediate effects of circadian dysregulation on tumor growth and provide targets for timed anticancer treatment

Y Lee, NF Lahens, S Zhang, J Bedont, JM Field… - PLoS …, 2019 - journals.plos.org
Circadian disruption has multiple pathological consequences, but the underlying
mechanisms are largely unknown. To address such mechanisms, we subjected transformed …