Allorecognition by T lymphocytes and allograft rejection

J Marino, J Paster, G Benichou - Frontiers in immunology, 2016 - frontiersin.org
Recognition of donor antigens by recipient T cells in secondary lymphoid organs initiates the
adaptive inflammatory immune response leading to the rejection of allogeneic transplants …

Extracellular vesicles in allograft rejection and tolerance

G Benichou, M Wang, K Ahrens, JC Madsen - Cellular immunology, 2020 - Elsevier
Extracellular vesicles (EVs), including exosomes, ectosomes and apoptotic vesicles, play an
essential role in communication between cells of the innate and adaptive immune systems …

Donor exosomes rather than passenger leukocytes initiate alloreactive T cell responses after transplantation

J Marino, MH Babiker-Mohamed… - Science …, 2016 - science.org
Transplantation of allogeneic organs and tissues represents a lifesaving procedure for a
variety of patients affected with end-stage diseases. Although current immunosuppressive …

A new I subregion (IJ) marked by a locus (Ia-4) controlling surface determinants on suppressor T lymphocytes.

DB Murphy, LA Herzenberg, KO Okumura… - The Journal of …, 1976 - rupress.org
In an accompanying publication we show that a subpopulation of T lymphocytes, which
includes allotype suppressor T cells, selectively expresses I-region determinants. In this …

A theory of regulation and self‐nonself discrimination in an immune network

GW Hoffmann - European journal of immunology, 1975 - Wiley Online Library
A mechanism is suggested for the regulation of the immune response that involves antigen‐
binding and anti‐idiotypic lymphocytes. The cross‐linking of receptors is postulated to be a …

Extracellular vesicles in liver transplantation: current evidence and future challenges

N De Stefano, A Calleri, AC Faini… - International Journal of …, 2023 - mdpi.com
Extracellular vesicles (EVs) are emerging as a promising field of research in liver disease.
EVs are small, membrane-bound vesicles that contain various bioactive molecules, such as …

[HTML][HTML] Intercellular transfer of MHC molecules in T cell alloimmunity and allotransplantation

G Benichou, HH Lancia - Biomedical Journal, 2024 - Elsevier
After transplantation of allogeneic tissues and organs, recognition by recipient T cells of
donor MHC molecules initiates the pro-inflammatory adaptive immune response leading to …

The histocompatibility-linked immune response genes

B Benacerraf, DH Katz - Advances in cancer research, 1975 - Elsevier
Publisher Summary This chapter provides information on histocompatibility-linked immune
response genes. The genetic study of the capacity to form specific immune responses has …

Selective expression of H-2 (i-region) loci controlling determinants on helper and suppressor T lymphocytes.

K Okumura, LA Herzenberg, DB Murphy… - The Journal of …, 1976 - rupress.org
Data presented here show that locidentify in the I-region of the H-2 gene complex are
selectively expressed in different functional T-cell subpopulations. These loci are closely …

Ly and Ia antigen phenotypes of T cells involved in delayed-type hypersensitivity and in suppression.

MA Vadas, JF Miller, IF McKenzie, SE Chism… - The Journal of …, 1976 - rupress.org
The Ly and Ia phenotypes of T lymphocytes involved in different functions were
characterized by the use of specific antisera. T cells responsible for delayed-type …