It has been two decades since the lipid raft hypothesis was first presented. Even today,
whether these nanoscale cholesterol-rich domains are present in cell membranes is not …

Super-resolution microscopy has emerged as a groundbreaking technique in cell biology,
enabling researchers to visualize proteins and their interactions with unprecedented spatial …

Fluorescence live-cell and super-resolution microscopy methods have considerably
advanced our understanding of the dynamics and mesoscale organization of macro …

Biochemistry in living cells is an emerging field of science. Current quantitative bioassays
are performed ex vivo, thus equilibrium constants and reaction rates of reactions occurring in …

SMeagol is a software tool to simulate highly realistic microscopy data based on spatial
systems biology models, in order to facilitate development, validation and optimization of …

Hyperlenses offer an appealing opportunity to unlock bioimaging beyond the diffraction limit
with conventional optics. Mapping hidden nanoscale spatiotemporal heterogeneities of lipid …

Technological innovation can drive scientific inquiry by allowing researchers to answer
questions that were once out of reach. Eukaryotic mRNA synthesis was not so long ago …

Probing dynamic processes occurring within the cell nucleus at the quantitative level has
long been a challenge in mammalian biology. Advances in bio-imaging techniques over the …

The early mouse embryo offers a phenomenal system to dissect how changes in the
mechanisms controlling cell fate are integrated with morphogenetic events at the single-cell …

Fluorescence fluctuation‐based methods are non‐invasive microscopy tools especially
suited for the study of dynamical aspects of biological processes. These methods examine …