Polydeoxyribonucleotide (PDRN) is a registered DNA-derived proprietary drug containing a
mixture of DNA fragments of molecular weights of 50 and 1500 kDa extracted mainly from …

Polynucleotides, complex molecules composed of nucleotides, have gained attention in
aesthetic medicine for their potential to regulate gene expression and promote tissue …

A multifunctional alginate/PDRN hydrogel system by ionic crosslinking and the Schiff base
reaction between oxidized alginate (OA) and PDRN was developed in the present study …

Conventional wound dressings have several shortcomings because they are unspecific and
partially effective for wound healing. To enhance the therapeutic efficiency of wound …

Nucleic acid-based agents have advantages in therapeutic efficacy and biological safety.
However, due to its facile degradability, it lacks an effective route of administration in wound …

Chronic diabetic wounds are difficult to treat due to imbalanced inflammatory responses,
high blood glucose levels, and bacterial infections. Novel therapeutic approaches based on …

The treatment of chronic diabetic wounds remains challenging due to the rapid bacterial
infection, severe inflammation, and insufficient angiogenesis. To address these challenges …

Sea cucumber viscera contain various naturally occurring active substances, but they are
often underutilized during sea cucumber processing. Polydeoxyribonucleotide (PDRN) is an …

A convenient method for the synthesis of the first generation PAMAM dendrimers based on
the thiacalix [4] arene has been developed for the first time. Three new PAMAM-calix …

Background Polynucleotides (PN) are increasingly used for the treatment of facial erythema
in the Republic of Korea. However, there are limited pre‐clinical and clinical data on the …