Chronic kidney disease (CKD) is defined by a low glomerular filtration rate or high
albuminuria, and affects 15–20% of adults globally. CKD increases the risk of various …

The gut microbiota contributes to host physiology through the production of a myriad of
metabolites. These metabolites exert their effects within the host as signalling molecules and …

In the last two decades, considerable interest has been shown in understanding the
development of the gut microbiota and its internal and external effects on the intestine, as …

Objective Patients with renal failure suffer from symptoms caused by uraemic toxins,
possibly of gut microbial origin, as deduced from studies in animals. The aim of the study is …

Numerous studies have indicated that the progression of chronic kidney disease (CKD) to
end-stage renal disease (ESRD) is strictly associated with the accumulation of toxic …

The kidney harbours different types of endothelia, each with specific structural and functional
characteristics. The glomerular endothelium, which is highly fenestrated and covered by a …

Background: Despite available clinical management strategies, chronic kidney disease
(CKD) is associated with severe morbidity and mortality worldwide, which beckons new …

Exercise is an effective strategy for diabetes management but is limited by the phenomenon
of exercise resistance (ie, the lack of or the adverse response to exercise on metabolic …

Depleted gut microbiome α-diversity is associated with several human diseases, but the
extent to which this is reflected in the host molecular phenotype is poorly understood. We …

Chronic kidney disease (CKD) is classified into five stages with kidney failure being the most
severe stage (stage G5). CKD conveys a high risk for coronary artery disease, heart failure …