Quercetin antagonizes the sedative effects of linalool, possibly through the GABAergic interaction pathway

MH Bappi, AAS Prottay, H Kamli, FA Sonia, MN Mia… - Molecules, 2023 - mdpi.com
Sedatives promote calmness or sleepiness during surgery or severely stressful events. In
addition, depression is a mental health issue that negatively affects emotional well-being. A …

[HTML][HTML] Sclareol exerts synergistic antidepressant effects with quercetin and caffeine, possibly suppressing GABAergic transmission in chicks

H Kamli, A Shaikh, MH Bappi, A Raposo… - Biomedicine & …, 2023 - Elsevier
This study evaluated the effects of sclareol (SCL) with or without caffeine (CAF) and
quercetin (QUR) using in-vivo and in-silico studies. For this, 5-day-old chicks weighing …

Quercetin increases the antidepressant‐like effects of sclareol and antagonizes diazepam in thiopental sodium‐induced sleeping mice: a possible GABAergic …

MH Bappi, MN Mia, SA Ansari, IA Ansari… - Phytotherapy …, 2024 - Wiley Online Library
Quercetin is the most common polyphenolic flavonoid present in fruits and vegetables
demonstrating versatile health‐promoting effects. This study aimed to examine the effects of …

Anxiolytic-like effect of succinic acid: a possible GABAergic intervention

MN Mia, SZ Smrity, MH Bappi, H Kamli, T Islam… - Food Bioscience, 2023 - Elsevier
In the modern era, physical and mental stress lead to anxiety at an alarming rate. Therefore,
searching for new lead compounds that deal with anxiety has a practical demand. Our study …

Assessment of sedative activity of fraxin: In vivo approach along with receptor binding affinity and molecular interaction with GABAergic system

SA Mukty, R Hasan, MS Bhuia, AK Saha… - Drug development …, 2024 - Wiley Online Library
Insomnia is a sleep disorder in which you have trouble falling and/or staying asleep. This
research aims to evaluate the sedative effects of fraxin (FX) on sleeping mice induced by …

[PDF][PDF] Antioxidant, anti-inflammatory, and anxiolytic-like effects of urena sinuata L.: in vitro, in vivo, and in silico studies

H Kamli, MH Bappi, T Islam, R Hossain… - J. Biol. Regul …, 2023 - researchgate.net
Background: Urena sinuata L. is a shrubby wild plant used for centuries in folk medicine to
treat bronchitis, rheumatism, fever, and waist pain. It is evident that it possesses antioxidant …

[HTML][HTML] Sclareol exerts an anti-inflammatory effect, possibly through COXs inhibition pathway: In vivo and in silico studies

AAS Prottay, MH Bappi, MS Akbor, AI Asha… - Pharmaceutical Science …, 2024 - Elsevier
Chronic and severe inflammation results in many diseases and disorders in humans.
Currently, available conventional anti-inflammatory drugs have numerous mild-to-severe …

Anti-inflammatory activity of d-pinitol possibly through inhibiting COX-2 enzyme: in vivo and in silico studies

MF Haque, HAS El-Nashar, MS Akbor, M Alfaifi… - Frontiers in …, 2024 - frontiersin.org
Introduction: D-pinitol, a naturally occurring inositol, has diverse biological activities like
antioxidant, antimicrobial and anticancer activities. This study aimed to evaluate anti …

Structural Characterization and Anti-Inflammatory Activity of Polysaccharides from Tremella fuciformis on Monosodium Urate-Stimulated RAW264.7 Macrophages

W Deng, L Wu, Z Xiao, Y Li, Z Zheng, S Chen - Foods, 2023 - mdpi.com
The structural characteristics and anti-inflammatory activity of Tremella fuciformis
polysaccharides (TFPs) were investigated. The study showed that TFPs were mainly …

[PDF][PDF] Synergistic hypnotic effects of sesamol and thymol possibly through GABAergic interaction pathway: in vivo and in silico studies

MS Akbor, MH Bappi, AAS Prottay… - J. Biol. Regul …, 2023 - researchgate.net
Background: Sleep is essential to human homeostasis and affects the immune system.
Sleep disorders are a group of conditions that disturb normal sleep patterns and can affect …