Patients with chronic liver disease and cirrhosis demonstrate a global mucosal immune
impairment, which is associated with altered gut microbiota composition and functionality …

Chronic liver disease is reaching epidemic proportions with the increasing prevalence of
obesity, nonalcoholic liver disease, and alcohol overuse worldwide. Most patients are not …

Organ transplantation is a life-saving treatment for patients with end-stage disease, but
survival rates after transplantation vary considerably. There is now increasing evidence that …

The rapid development of sonodynamic therapy (SDT) provides a promising strategy for
treating deep-seated multidrug-resistant (MDR) bacterial infection. However, the extreme …

Metabolites produced by the intestinal microbiome modulate mucosal immune defenses and
optimize epithelial barrier function. Intestinal dysbiosis, including loss of intestinal …

Renal transplantation is life-changing in many aspects. This includes changes to the gut
microbiome likely due to exposure to immunosuppressive drugs and antibiotics. As a …

Cirrhosis is characterized by inflammation, degeneration, and fibrosis of liver tissue. Along
with being the most common cause of liver failure and liver transplant, cirrhosis is a …

Microbiome alterations are emerging as one of the most important factors that influence the
course of alcohol use disorder (AUD). Recent advances in bioinformatics enable more …

The human gut is host to a diverse range of microorganisms that offer protection against
colonization by multidrug-resistant bacteria. Antibiotic use, medications, health conditions …

Background Gut colonisation by extended-spectrum β-lactamase (ESBL)-producing
Escherichia coli is a risk factor for developing overt infection. The gut microbiome can …