Antibiotic residues are being continuously recognized in the aquatic environment and in
food. Though the concentration of antibiotic residues is typically low, adverse effects on the …

Antimicrobial resistance (AR) is a problem that threatens the search for adequate safe and
effective antibiotic therapy against multi-resistant bacteria like methicillin-resistant …

A new method using high performance liquid chromatography coupled with electrospray
mass spectrometry is described for the quantification of PBMC concentration of tyrosine …

The therapeutic drug monitoring (TDM) of pharmaceutical drugs with narrow therapeutic
ranges is of great importance in the clinical setting. It provides useful information towards the …

A highly sensitive and rapid liquid chromatography tandem mass spectrometry (LC–MS/MS)
method has been developed to measure the levels of the antitubercular drug rifampicin (RIF) …

Amikacin (AMK) is one of the commonly used aminoglycoside antibiotics, introduced for
clinical use in patients suffering from bacterial infections especially life-threatening gram …

Background There are currently few data concerning the cerebrospinal fluid (CSF)
penetration of daptomycin in patients with healthcare-associated meningitis. This study aims …

Background Fluoroquinolones and rifampicin are antibiotics frequently used for the
treatment of osteoarticular infections, and their therapeutic drug monitoring is recommended …

Infections, including sepsis, are associated with high mortality rates in critically ill patients in
the intensive care unit (ICU). Appropriate antibiotic selection and adequate dosing are …

Background: Amikacin and kanamycin are frequently used in the treatment of multidrug-
resistant TB. The current commercially available immunoassay is unable to analyze …