Vitamin E and cancer prevention: Studies with different forms of tocopherols and tocotrienols

CS Yang, P Luo, Z Zeng, H Wang… - Molecular …, 2020 - Wiley Online Library
Abstract α‐Tocopherol (α‐T) is the major form of vitamin E (VE) in animals and has the
highest activity in carrying out the essential antioxidant functions of VE. Because of the …

Tocotrienols: The promising analogues of vitamin E for cancer therapeutics

BL Sailo, K Banik, G Padmavathi, M Javadi… - Pharmacological …, 2018 - Elsevier
Despite the significant advancements in the diagnosis and treatment of cancer, it still
remains one of the most fatal diseases in the world due to the lack of sensitive diagnosis …

Therapeutic potential of palm oil vitamin E-derived tocotrienols in inflammation and chronic diseases: Evidence from preclinical and clinical studies

Z Zainal, H Khaza'ai, AK Radhakrishnan… - Food Research …, 2022 - Elsevier
Palm oil is rich in tocotrienols (T3s), a type of vitamin E that has garnered considerable
research interest as it exhibits anti-inflammatory as well as antioxidant characteristics that …

Revisiting the therapeutic potential of tocotrienol

R Ranasinghe, M Mathai, A Zulli - Biofactors, 2022 - Wiley Online Library
The therapeutic potential of the tocotrienol group stems from its nutraceutical properties as a
dietary supplement. It is largely considered to be safe when consumed at low doses for …

Phytochemical Profile of the Ethanol Extract of Malvaviscus arboreus Red Flower and Investigation of the Antioxidant, Antimicrobial, and Cytotoxic Activities

HSS Gazwi, NA Shoeib, ME Mahmoud, OIA Soltan… - Antibiotics, 2022 - mdpi.com
Flowers are rich sources of bioactive antimicrobial, antioxidant, and anticancer components.
This study aimed to determine the constituents of the ethanol extract of Malvaviscus …

Potential role of tocotrienols on non-communicable diseases: a review of current evidence

SK Wong, Y Kamisah, N Mohamed, N Muhammad… - Nutrients, 2020 - mdpi.com
Tocotrienol (T3) is a subfamily of vitamin E known for its wide array of medicinal properties.
This review aimed to summarize the health benefits of T3, particularly in prevention or …

Exceedingly higher co-loading of curcumin and paclitaxel onto polymer-functionalized reduced graphene oxide for highly potent synergistic anticancer treatment

K Muthoosamy, IB Abubakar, RG Bai, HS Loh… - Scientific reports, 2016 - nature.com
Metastasis of lung carcinoma to breast and vice versa accounts for one of the vast majority of
cancer deaths. Synergistic treatments are proven to be the effective method to inhibit …

In vitro Antiproliferative and Apoptosis Inducing Effect of Allium atroviolaceum Bulb Extract on Breast, Cervical, and Liver Cancer Cells

S Khazaei, NM Esa, V Ramachandran… - Frontiers in …, 2017 - frontiersin.org
Natural products are considered potent sources for novel drug discovery and development.
The multiple therapeutic effects of natural compounds in traditional medicine motivate us to …

Beta-tocotrienol exhibits more cytotoxic effects than gamma-tocotrienol on breast cancer cells by promoting apoptosis via a P53-independent PI3-kinase dependent …

M Idriss, MH Hodroj, R Fakhoury, S Rizk - Biomolecules, 2020 - mdpi.com
Studies on tocotrienols have progressively revealed the benefits of these vitamin E isoforms
on human health. Beta-tocotrienol (beta-T3) is known to be less available in nature …

Efficient secretory production of δ-tocotrienol by combining pathway modularization and transportation engineering

X Jiao, Q Bian, T Feng, X Lyu, H Yu… - Journal of Agricultural …, 2023 - ACS Publications
The vitamin E component δ-tocotrienol has shown impressive activities in radioprotection,
neuroprotection, and cholesterol reduction. Its production is limited by the low content in …