Mobile genetic elements associated with antimicrobial resistance

SR Partridge, SM Kwong, N Firth… - Clinical microbiology …, 2018 - Am Soc Microbiol
Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …

Bacterial genome instability

E Darmon, DRF Leach - Microbiology and Molecular Biology …, 2014 - Am Soc Microbiol
Bacterial genomes are remarkably stable from one generation to the next but are plastic on
an evolutionary time scale, substantially shaped by horizontal gene transfer, genome …

Gene cassettes and cassette arrays in mobile resistance integrons

SR Partridge, G Tsafnat, E Coiera… - FEMS microbiology …, 2009 - academic.oup.com
Gene cassettes are small mobile elements, consisting of little more than a single gene and
recombination site, which are captured by larger elements called integrons. Several …

Conjugative and mobilizable genomic islands in bacteria: evolution and diversity

X Bellanger, S Payot… - FEMS Microbiology …, 2014 - academic.oup.com
Horizontal transfer of genomic islands (GEIs), that is, chromosomal regions encoding
functions that can be advantageous for the host, plays a key role in bacterial evolution, but …

Group II introns: mobile ribozymes that invade DNA

AM Lambowitz, S Zimmerly - Cold Spring Harbor …, 2011 - cshperspectives.cshlp.org
Group II introns are mobile ribozymes that self-splice from precursor RNAs to yield excised
intron lariat RNAs, which then invade new genomic DNA sites by reverse splicing. The …

Evolution of group II introns

S Zimmerly, C Semper - Mobile DNA, 2015 - Springer
Present in the genomes of bacteria and eukaryotic organelles, group II introns are an
ancient class of ribozymes and retroelements that are believed to have been the ancestors …

Mobile bacterial group II introns at the crux of eukaryotic evolution

AM Lambowitz, M Belfort - Mobile DNA III, 2015 - Wiley Online Library
Group II introns are remarkable mobile retroelements that use the combined activities of an
autocatalytic RNA and an intron‐encoded reverse transcriptase (RT) to propagate efficiently …

Cis-and trans-splicing of group II introns in plant mitochondria

L Bonen - Mitochondrion, 2008 - Elsevier
Group II-type introns in the mitochondrial genes of flowering plants belong to the ribozymic,
mobile retroelement family, but not all exhibit conventional structural features and some …

Group II intron self-splicing

AM Pyle - Annual Review of Biophysics, 2016 - annualreviews.org
Group II introns are large, autocatalytic ribozymes that catalyze RNA splicing and
retrotransposition. Splicing by group II introns plays a major role in the metabolism of plants …

Biotechnological applications of mobile group II introns and their reverse transcriptases: gene targeting, RNA-seq, and non-coding RNA analysis

PJ Enyeart, G Mohr, AD Ellington, AM Lambowitz - Mobile DNA, 2014 - Springer
Mobile group II introns are bacterial retrotransposons that combine the activities of an
autocatalytic intron RNA (a ribozyme) and an intron-encoded reverse transcriptase to insert …