Imaging has played a variety of roles in the study of Alzheimer disease (AD) over the past
four decades. Initially, computed tomography (CT) and then magnetic resonance imaging …

The hallmark clinical symptom of early Alzheimer's disease (AD) is episodic memory
impairment. Recent functional imaging studies suggest that memory function is subserved …

Alzheimer's disease (AD) is a form of brain disorder that causes functions' loss in a person's
daily activity. Due to the tremendous progress of Alzheimer's patients and the lack of …

Alzheimer disease (AD) is the most common cause of dementia in the elderly. Autopsy case
series on the sequential accumulation of neurofibrillary bundles and amyloid plaques, as …

The role of APOE in the risk of Alzheimer's disease (AD) has largely focused on its effects on
AD pathological processes. However, there are increasing data that APOE genotype affects …

Functional magnetic resonance imaging (fMRI) is a relative newcomer in the field of
biomarkers for Alzheimer's disease (AD). fMRI has several potential advantages, particularly …

Increasing age and carrying an APOEε4 allele are well established risk factors for
Alzheimer's disease (AD). The earlier age of onset of AD observed in ε4-carriers may reflect …

APOE-4 is the strongest genetic risk factor for Alzheimer's disease (AD), and is associated
with an increase in the levels of amyloid deposition and an early age of onset. Recent data …

Research on apolipoprotein E (APOE) has consistently revealed a relationship between the
gene′ s ε4 allele and risk for development of Alzheimer′ s disease (AD). However …

Functional MRI (fMRI) studies of mild cognitive impairment (MCI) and Alzheimer's disease
(AD) have begun to reveal abnormalities in large-scale memory and cognitive brain …