[HTML][HTML] Health position paper and redox perspectives-Disease burden by transportation noise

M Sørensen, G Pershagen, JD Thacher, T Lanki… - Redox Biology, 2024 - Elsevier
Transportation noise is a ubiquitous urban exposure. In 2018, the World Health Organization
concluded that chronic exposure to road traffic noise is a risk factor for ischemic heart …

Ischemic heart disease and heart failure: role of coronary ion channels

P Severino, A D'Amato, M Pucci, F Infusino… - International journal of …, 2020 - mdpi.com
Heart failure is a complex syndrome responsible for high rates of death and hospitalization.
Ischemic heart disease is one of the most frequent causes of heart failure and it is normally …

KV channels and the regulation of vascular smooth muscle tone

WF Jackson - Microcirculation, 2018 - Wiley Online Library
VSMC s in resistance arteries and arterioles express a diverse array of KV channels with
members of the KV 1, KV 2 and KV 7 families being particularly important. Members of the …

Adenosine and adenosine receptor-mediated action in coronary microcirculation

Y Zhang, B Wernly, X Cao, SJ Mustafa, Y Tang… - Basic Research in …, 2021 - Springer
Adenosine is an ubiquitous extracellular signaling molecule and plays a fundamental role in
the regulation of coronary microcirculation through activation of adenosine receptors (ARs) …

Inhibition of mitochondrial oxidative damage improves reendothelialization capacity of endothelial progenitor cells via SIRT3 (Sirtuin 3)-enhanced SOD2 (superoxide …

J He, X Liu, C Su, F Wu, J Sun, J Zhang… - … and Vascular Biology, 2019 - Am Heart Assoc
Objective: Dysfunction of endothelial progenitor cells (EPCs) leads to impaired endothelial
repair capacity in patients with hypertension, but the mechanisms remain incompletely …

Regulation of voltage‐gated potassium channels in vascular smooth muscle during hypertension and metabolic disorders

M Nieves‐Cintrón, AU Syed, MA Nystoriak… - …, 2018 - Wiley Online Library
Voltage‐gated potassium (KV) channels are key regulators of vascular smooth muscle
contractility and vascular tone, and thus have major influence on the microcirculation. KV …

Ion channels and vascular diseases

J Cheng, J Wen, N Wang, C Wang, Q Xu… - … , and vascular biology, 2019 - Am Heart Assoc
Transient receptor potential (TRP) channels are not only the major contributors to Ca2+
signaling but also the targets of Ca2+ signaling. Ca2+ regulation of TRP channels involves 3 …

Disturbed redox homeostasis in oxidative distress: a molecular link from chronic psychosocial work stress to coronary heart disease?

J Siegrist, H Sies - Circulation Research, 2017 - Am Heart Assoc
104 Circulation Research July 7, 2017 environments by applying a stress-theoretical model,
with 2 stressors, job strain and effort–reward imbalance. Job strain considers threat to …

Impaired BKCa channel function in native vascular smooth muscle from humans with type 2 diabetes

M Nieves-Cintrón, AU Syed, OR Buonarati, RR Rigor… - Scientific reports, 2017 - nature.com
Abstract Large-conductance Ca2+-activated potassium (BKCa) channels are key
determinants of vascular smooth muscle excitability. Impaired BKCa channel function …

Pyridine nucleotide redox potential in coronary smooth muscle couples myocardial blood flow to cardiac metabolism

MM Dwenger, SM Raph, ML Reyzer… - Nature …, 2022 - nature.com
Adequate oxygen delivery to the heart during stress is essential for sustaining cardiac
function. Acute increases in myocardial oxygen demand evoke coronary vasodilation and …