Behavioral and neurobiological mechanisms of pavlovian and instrumental extinction learning
This article reviews the behavioral neuroscience of extinction, the phenomenon in which a
behavior that has been acquired through Pavlovian or instrumental (operant) learning …
behavior that has been acquired through Pavlovian or instrumental (operant) learning …
Immediate early genes, memory and psychiatric disorders: focus on c-Fos, Egr1 and Arc
Many psychiatric disorders, despite their specific characteristics, share deficits in the
cognitive domain including executive functions, emotional control and memory. However …
cognitive domain including executive functions, emotional control and memory. However …
Surviving threats: neural circuit and computational implications of a new taxonomy of defensive behaviour
Research on defensive behaviour in mammals has in recent years focused on elicited
reactions; however, organisms also make active choices when responding to danger. We …
reactions; however, organisms also make active choices when responding to danger. We …
The birth, death and resurrection of avoidance: a reconceptualization of a troubled paradigm
Research on avoidance conditioning began in the late 1930s as a way to use laboratory
experiments to better understand uncontrollable fear and anxiety. Avoidance was initially …
experiments to better understand uncontrollable fear and anxiety. Avoidance was initially …
Rethinking avoidance: Toward a balanced approach to avoidance in treating anxiety disorders
SG Hofmann, AC Hay - Journal of anxiety disorders, 2018 - Elsevier
Avoidance is typically considered a maladaptive behavioral response to excessive fear and
anxiety, leading to the maintenance of anxiety disorders. Exposure is a core element of …
anxiety, leading to the maintenance of anxiety disorders. Exposure is a core element of …
Influences of early‐life stress on frontolimbic circuitry: Harnessing a dimensional approach to elucidate the effects of heterogeneity in stress exposure
EM Cohodes, ER Kitt… - Developmental …, 2021 - Wiley Online Library
Early‐life stress confers profound and lasting risk for developing cognitive, social, emotional,
and physical health problems. The effects of stress on the developing brain contribute to this …
and physical health problems. The effects of stress on the developing brain contribute to this …
Prefrontal-hippocampal interactions supporting the extinction of emotional memories: the retrieval stopping model
MC Anderson, SB Floresco - Neuropsychopharmacology, 2022 - nature.com
Neuroimaging has revealed robust interactions between the prefrontal cortex and the
hippocampus when people stop memory retrieval. Efforts to stop retrieval can arise when …
hippocampus when people stop memory retrieval. Efforts to stop retrieval can arise when …
Prefrontal cortical dynorphin peptidergic transmission constrains threat-driven behavioral and network states
Prefrontal cortical (PFC) circuits provide top-down control of threat reactivity. This includes
ventromedial PFC (vmPFC) circuitry, which plays a role in suppressing fear-related …
ventromedial PFC (vmPFC) circuitry, which plays a role in suppressing fear-related …
Low-cost avoidance behaviors are resistant to fear extinction in humans
B Vervliet, E Indekeu - Frontiers in behavioral neuroscience, 2015 - frontiersin.org
Elevated levels of fear and avoidance are core symptoms across the anxiety disorders. It has
long been known that fear serves to motivate avoidance. Consequently, fear extinction has …
long been known that fear serves to motivate avoidance. Consequently, fear extinction has …
BehaviorDEPOT is a simple, flexible tool for automated behavioral detection based on markerless pose tracking
Quantitative descriptions of animal behavior are essential to study the neural substrates of
cognitive and emotional processes. Analyses of naturalistic behaviors are often performed …
cognitive and emotional processes. Analyses of naturalistic behaviors are often performed …