Dementia prevention, intervention, and care

G Livingston, A Sommerlad, V Orgeta, SG Costafreda… - The lancet, 2017 - thelancet.com
Executive summary Acting now on dementia prevention, intervention, and care will vastly
improve living and dying for individuals with dementia and their families, and in doing so …

The feasibility and effect of deprescribing in older adults on mortality and health: a systematic review and meta‐analysis

AT Page, RM Clifford, K Potter… - British journal of …, 2016 - Wiley Online Library
Aims Deprescribing is a suggested intervention to reverse the potential iatrogenic harms of
inappropriate polypharmacy. The review aimed to determine whether or not deprescribing is …

Health outcomes of deprescribing interventions among older residents in nursing homes: a systematic review and meta-analysis

CH Kua, VSL Mak, SWH Lee - Journal of the American Medical Directors …, 2019 - Elsevier
Objectives Deprescribing is effective in addressing concerns relating to polypharmacy in
residents of nursing homes. However, the clinical outcomes of deprescribing interventions …

Effect of citalopram on agitation in Alzheimer disease: the CitAD randomized clinical trial

AP Porsteinsson, LT Drye, BG Pollock, DP Devanand… - Jama, 2014 - jamanetwork.com
Importance Agitation is common, persistent, and associated with adverse consequences for
patients with Alzheimer disease. Pharmacological treatment options, including …

Withdrawal symptoms after selective serotonin reuptake inhibitor discontinuation: a systematic review

GA Fava, A Gatti, C Belaise, J Guidi… - Psychotherapy and …, 2015 - karger.com
Background: Selective serotonin reuptake inhibitors (SSRI) are widely used in medical
practice. They have been associated with a broad range of symptoms, whose clinical …

Comparative efficacy of interventions for reducing symptoms of depression in people with dementia: systematic review and network meta-analysis

JA Watt, Z Goodarzi, AA Veroniki, V Nincic, PA Khan… - bmj, 2021 - bmj.com
Objective To describe the comparative efficacy of drug and non-drug interventions for
reducing symptoms of depression in people with dementia who experience depression as a …

Comparative efficacy of interventions for aggressive and agitated behaviors in dementia: a systematic review and network meta-analysis

JA Watt, Z Goodarzi, AA Veroniki, V Nincic… - Annals of internal …, 2019 - acpjournals.org
Background: Both pharmacologic and nonpharmacologic interventions are used to treat
neuropsychiatric symptoms in persons with dementia. Purpose: To summarize the …

Efficacy of antidepressants for depression in Alzheimer's disease: systematic review and meta-analysis

V Orgeta, N Tabet, R Nilforooshan… - Journal of Alzheimer's …, 2017 - content.iospress.com
Background: Depression is common in people with Alzheimer's disease (AD) affecting
overall outcomes and decreasing quality of life. Although depression in AD is primarily …

A European Academy of Neurology guideline on medical management issues in dementia

KS Frederiksen, C Cooper, GB Frisoni… - European journal of …, 2020 - Wiley Online Library
Background and purpose Dementia is one of the most common disorders and is associated
with increased morbidity, mortality and decreased quality of life. The present guideline …

Behavioral and psychological symptoms in Alzheimer's dementia and vascular dementia

WJ Deardorff, GT Grossberg - Handbook of clinical neurology, 2019 - Elsevier
Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent and
represent a significant burden for patients and their caregivers. Early recognition and …