[HTML][HTML] Broad targeting of angiogenesis for cancer prevention and therapy

Z Wang, C Dabrosin, X Yin, MM Fuster, A Arreola… - Seminars in cancer …, 2015 - Elsevier
Deregulation of angiogenesis–the growth of new blood vessels from an existing vasculature–
is a main driving force in many severe human diseases including cancer. As such, tumor …

[HTML][HTML] Silymarin (milk thistle extract) as a therapeutic agent in gastrointestinal cancer

M Fallah, A Davoodvandi, S Nikmanzar, S Aghili… - Biomedicine & …, 2021 - Elsevier
Silymarin contains a group of closely-related flavonolignan compounds including silibinin,
and is extracted from Silybum marianum species, also called milk thistle. Silymarin has been …

Path of Silibinin from diet to medicine: A dietary polyphenolic flavonoid having potential anti-cancer therapeutic significance

HS Tuli, S Mittal, D Aggarwal, G Parashar… - Seminars in Cancer …, 2021 - Elsevier
In the last few decades, targeting cancer by the use of dietary phytochemicals has gained
enormous attention. The plausible reason and believe or mind set behind this fact is …

Characterization of the hydrochemistry, scaling and corrosivity tendencies, and irrigation suitability of the water of the Rivers Karawa and Iyiaji

OL Alum, HO Abugu, VC Onwujiogu, AL Ezugwu… - Sustainability, 2023 - mdpi.com
Assessing water quality is necessary to ascertain its viability for domestic, industrial, and
agricultural purposes. A total of 48 water samples were, respectively, drawn from the Rivers …

Silymarin in the prevention and treatment of liver diseases and primary liver cancer

J Fehér, G Lengyel - Current pharmaceutical biotechnology, 2012 - ingentaconnect.com
In chronic liver diseases caused by oxidative stress (alcoholic and non-alcoholic fatty liver
diseases, drug-and chemical-induced hepatic toxicity), the antioxidant medicines such as …

Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer

G Deep, R Agarwal - Cancer and Metastasis Reviews, 2010 - Springer
Cancer is a major health problem around the world. Research efforts in the last few decades
have been successful in providing better and effective treatments against both early stage …

Silymarin and cancer: A dual strategy in both in chemoprevention and chemosensitivity

D Delmas, J Xiao, A Vejux, V Aires - Molecules, 2020 - mdpi.com
Silymarin extracted from milk thistle consisting of flavonolignan silybin has shown
chemopreventive and chemosensitizing activity against various cancers. The present review …

[HTML][HTML] Potential phytochemicals in the fight against skin cancer: Current landscape and future perspectives

J Iqbal, BA Abbasi, R Ahmad, R Batool… - Biomedicine & …, 2019 - Elsevier
Skin cancer is a life threatening disease and their prevalence and risk has been increasing
over the past three decades causing significant loss to human health worldwide. Mostly skin …

Silibinin to improve cancer therapeutic, as an apoptotic inducer, autophagy modulator, cell cycle inhibitor, and microRNAs regulator

Z Jahanafrooz, N Motamed, B Rinner, A Mokhtarzadeh… - Life sciences, 2018 - Elsevier
Silibinin is a natural plant polyphenol with high antioxidant and anticancer properties, which
causes broad-spectrum efficacy against cancer, including cell cycle arrest and apoptosis in …

Modulatory effects of silibinin in various cell signaling pathways against liver disorders and cancer–A comprehensive review

N Polachi, G Bai, T Li, Y Chu, X Wang, S Li… - European journal of …, 2016 - Elsevier
Silibinin, a natural flavanone, derived from the milk thistle plant (Silybum marianum), was
illustrated for several medicinal uses such as liver-protective, anti-oxidant, anti-cancer, anti …